ArticleNature communications2019
The evolution of sex determination associated with a chromosomal inversion.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 108 citations in OpenAlex.
- Evolution of a ZW sex determination system in sticklebacks.Science advances · 2026Article
- Divergent selection, recombination variability, and noncoding introgression drive speciation and adaptation in threadfin Eleutheronema.Communications biology · 2025Article
- Investigating the evolution of large meiotic rings of multiple X and Y sex chromosomes in two Leptodactylus frog species (Anura, Leptodactylidae).Communications biology · 2025Article
- Analyses of contiguous reference genomes of Amaranthus tuberculatus highlight the landscape of the sex-associated region and PEBP gene family diversity.BMC genomics · 2025Article
- A Y-linked duplication of anti-Mullerian hormone is the sex determination gene in threespine stickleback.PLoS genetics · 2025Article
- Chromosomal Inversions Mediated by Tandem Insertions of Transposable Elements.Genome biology and evolution · 2025Article
- Dynamics of Deleterious Mutations and Purifying Selection in Small Population Isolates.Molecular biology and evolution · 2025Article
- The fourspine stickleback (Apeltes quadracus) has an XY sex chromosome system with polymorphic inversions on both X and Y chromosomes.PLoS genetics · 2025Article
- Allelic variation and duplication of the dmrt1 were associated with sex chromosome turnover in three representative Scatophagidae fish species.Communications biology · 2025Article
- The Cause-Effect Model of Master Sex Determination Gene Acquisition and the Evolution of Sex Chromosomes.International journal of molecular sciences · 2025Review
- Large inversions in Lake Malawi cichlids are associated with habitat preference, lineage, and sex determination.bioRxiv : the preprint server for biology · 2025Article
- Evidence for Variation in the Genetic Basis of Sex Determination in Brook Stickleback (Ecology and evolution · 2025Article
- The genome of Hippophae salicifolia provides new insights into the sexual differentiation of sea buckthorn.GigaScience · 2025Article
- Sex chromosome turnover in hybridizing stickleback lineages.Evolution letters · 2024Article
- Improved assembly of the Pungitius pungitius reference genome.G3 (Bethesda, Md.) · 2024Article
- Sex chromosome turnover plays an important role in the maintenance of barriers to post-speciation introgression in willows.Evolution letters · 2024Article
- Identification and characterization of a new species of Taxus - Taxus qinlingensis by multiple taxonomic methods.BMC plant biology · 2024Article
- Secondary Contact, Introgressive Hybridization, and Genome Stabilization in Sticklebacks.Molecular biology and evolution · 2024Article
- Evolution of a ZW sex chromosome system in willows.Nature communications · 2023Article
- De Novo Mutation Rates in Sticklebacks.Molecular biology and evolution · 2023Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sex determination is a fundamentally important and highly diversified biological process, yet the mechanisms behind the origin of this diversity are mostly unknown. Here we suggest that the evolution of sex determination systems can be driven by a chromosomal inversion. We show that an XY system evolved recently in particular nine-spined stickleback (Pungitius pungitius) populations, which arose from ancient hybridization between two divergent lineages. Our phylogenetic and genetic mapping analyses indicate that the XY system is formed in a large inversion that is associated with hybrid sterility between the divergent lineages. We suggest that a new male-determining gene evolved in the inversion in response to selection against impaired male fertility in a hybridized population. Given that inversions are often associated with hybrid incompatibility in animals and plants, they might frequently contribute to the diversification of sex determination systems.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.