ArticleAJNR. American journal of neuroradiology2019
MRI Quantitative T2* Mapping to Predict Dominant Composition of In Vitro Thrombus.
Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Quantitative characterization of composition heterogeneity in complex aortic thrombus using cardiac magnetic resonance: a case description.Quantitative imaging in medicine and surgery · 2025Article
- Ironing out differences in attenuation and blooming artifact in acute stroke thrombi.Scientific reports · 2025Article
- Deep learning prediction of stroke thrombus red blood cell content from multiparametric MRI.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024Article
- Impedance-based sensors discriminate among different types of blood thrombi with very high specificity and sensitivity.Journal of neurointerventional surgery · 2023Article
- Magnetic resonance imaging quantitative T2* mapping to predict the red blood cell content of in vivo thrombi retrieved from patients with large vessel occlusions in acute ischemic stroke.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2022Article
- In Vitro Study of Blood Clot Identification and Composition Assessment by Different Magnetic Resonance Sequences.Cureus · 2021Article
- Impact of Clot Shape on Successful M1 Endovascular Reperfusion.Frontiers in neurology · 2021Article
- Biomechanics and hemodynamics of stent-retrievers.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020Review
- Clot Analog Attenuation in Non-contrast CT Predicts Histology: an Experimental Study Using Machine Learning.Translational stroke research · 2020Article
- Imaging Clot Characteristics in Stroke and its Possible Implication on Treatment.Clinical neuroradiology · 2020Review
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10 authors.
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Abstract
background and purposeMR imaging quantitative T2* mapping, which provides information about thrombus composition and specifically the red blood cell content, may be obtained in the setting of acute ischemic stroke before treatment. This could be useful to adapt the endovascular strategy. We aimed to analyze the red blood cell content of in vitro thrombi in relation to the thrombus-T2* relaxation time. MATERIALS AND
methodsThirty-five thrombus analogs of different compositions were scanned with an MR imaging quantitative T2* mapping sequence. Two radiologists, blinded to thrombus composition, measured the thrombus-T2* relaxation time twice at an interval of 2 weeks. Quantitative histologic evaluations of red blood cell content were performed. Inter- and intraobserver reproducibility of the thrombus-T2* relaxation time was assessed by calculating intraclass correlation coefficients. Finally, a Spearman product moment correlation between the thrombus-T2* relaxation time and red blood cell content was performed.
resultsThe median thrombus-T2* relaxation time was 78.5 ms (range, 16-268 ms; interquartile range, 60.5 ms). The median red blood cell content was 55% (range, 0%-100%; interquartile range, 75%). Inter- and intraobserver reproducibility of the thrombus-T2* relaxation time was excellent (>0.9). The Spearman rank correlation test found a significant inverse correlation between thrombus-T2* relaxation time and red blood cell content (ρ = -0.834,
conclusionsMR imaging quantitative T2* mapping can reliably identify the thrombus red blood cell content in vitro. This fast, easy-to-use sequence could be implemented in routine practice to predict stroke etiology and adapt devices or techniques for endovascular treatment of acute ischemic stroke.
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