Evidence map›Paper›PMID 30635285›Full record

ArticleBlood2019

Successful donor engraftment and repair of the blood-brain barrier in cerebral adrenoleukodystrophy.

Paul J Orchard, David R Nascene, Weston P Miller, Ashish Gupta, Dan Kenney-Jung, Troy C Lund

Open access · bronzeAbstract read
In one paragraph

Article in Blood, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Promoting donor microglial replacement through augmented conditioning or radiation sensitivity.Molecular therapy : the journal of the American Society of Gene Therapy · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Research (Washington, D.C.) · 2022
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Paul J OrchardDivision of Pediatric Blood and Marrow Transplant, Department of Pediatrics, University of Minnesota, Minneapolis, MN.
David R NasceneDepartment of Diagnostic Radiology, University of Minnesota Medical Center, Minneapolis, MN.
Weston P MillerSagamo Therapeutics, Richmond, CA; and.
Ashish GuptaDivision of Pediatric Blood and Marrow Transplant, Department of Pediatrics, University of Minnesota, Minneapolis, MN.ORCID 0000-0001-5679-5533
Dan Kenney-JungDepartment of Neurology, University of Minnesota Medical Center, Minneapolis, MN.
Troy C LundDivision of Pediatric Blood and Marrow Transplant, Department of Pediatrics, University of Minnesota, Minneapolis, MN.
University of Minnesota · USUniversity of Minnesota Medical Center · US

Funding

Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Douglas Yee · 1998 to 2026
$100.4M
NCI NIH HHS P30 CA077598
6 · The paper itself

Abstract

Adrenoleukodystrophy (ALD) is caused by mutations within the X-linked

Indexed as

Hematopoietic Stem Cell TransplantationTissue DonorsAdolescentAdrenoleukodystrophyAdultATP Binding Cassette Transporter, Subfamily D, Member 1Biological TransportBlood-Brain BarrierChildChild, PreschoolDisease ProgressionFollow-Up StudiesGadoliniumGraft RejectionGraft SurvivalHumansABCD1 protein, humanATP Binding Cassette Transporter, Subfamily D, Member 1Gadolinium

Identifiers

PMID30635285
PMCPMC6440119
OpenAlexW2909753998

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.