ArticleThe Journal of allergy and clinical immunology2019
Racial disparities in asthma-related health care use in the National Heart, Lung, and Blood Institute's Severe Asthma Research Program.
Article in The Journal of allergy and clinical immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05246267 (Dupilumab Treatment Effects in an Ethnically Diverse Population With Chronic Rhinosinusitis With Nasal Polyposis), which is not on this map. Cited by 55 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Dupilumab Treatment Effects in an Ethnically Diverse Population With Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)
Who cites it
55 citing papers in PubMed, 92 citations in OpenAlex.
- Tezepelumab in real-world US patients with severe asthma across phenotypes and underrepresented populations: the phase 4 PASSAGE study.American journal of respiratory and critical care medicine · 2026Trial
- Effect of the Telemedicine Enhanced Asthma Management-Uniting Providers (TEAM-UP) Program on Asthma Outcomes: A Randomized Clinical Trial.The Journal of pediatrics · 2026Trial
- Effectiveness and Safety of Tezepelumab in a Diverse Population of US Patients with Severe Asthma: Initial Results of the PASSAGE Study.Advances in therapy · 2025Trial
- Evaluating inhaler education interventions for hospitalized children with asthma: A randomized controlled trial.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2023Trial
- Clustering of self-reported social and environmental risk factors identifies vulnerable subgroups with increased asthma morbidity.The journal of allergy and clinical immunology. Global · 2026Article
- Review
- Pediatric asthma specialist care utilization among marginalized children with poorly controlled asthma.The Journal of asthma : official journal of the Association for the Care of Asthma · 2026Article
- The role of housing markets in producing respiratory health disparities.Lancet regional health. Americas · 2025Review
- Cost-related barriers to medication use among diverse participants with obesity-associated asthma.Journal of managed care & specialty pharmacy · 2025Article
- Detection and prediction of real-world severe asthma phenotypes by application of machine learning to electronic health records.The journal of allergy and clinical immunology. Global · 2025Article
- Multicohort Analysis of Bronchial Epithelial Cell Expression in Healthy Subjects and Patients with Asthma Reveals Four Clinically Distinct Clusters.American journal of respiratory cell and molecular biology · 2025Article
- Peripheral eosinophil count as a biomarker for asthma exacerbation severity in acute care settings.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2025Article
- Integrating geospatial data with birth cohorts to explore social determinants of health and asthma.The Journal of allergy and clinical immunology · 2025Review
- School-based asthma therapy: Improving medication adherence, asthma control, and health care utilization.The journal of allergy and clinical immunology. Global · 2025Article
- Disparities in Clinical Outcomes Observed Within Electronic Health Record Data From a Statewide Cohort of Pulmonary Arterial Hypertension Patients.Pulmonary circulation · 2025Article
- Recommendations for Clinicians to Combat Environmental Disparities in Pediatric Asthma: A Review.Chest · 2024Review
- A novel tool using social and environmental determinants of health to assess pediatric asthma in the emergency department.Journal of the American College of Emergency Physicians open · 2024Article
- The Role of Neighborhood Air Pollution in Disparate Racial and Ethnic Asthma Acute Care Use.American journal of respiratory and critical care medicine · 2024Article
- Plasma metabolomics identifies differing endotypes of recurrent wheezing in preschool children differentiated by symptoms and social disadvantage.Scientific reports · 2024Article
- Factors associated with emergency department visits for asthma resulting in hospital admission-United States, 2020.The Journal of asthma : official journal of the Association for the Care of Asthma · 2024Article
Corrections and comments
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Authors and funding
25 authors at 13 institutions in 1 country.
Funding
Abstract
backgroundDespite advances in asthma care, disparities persist. Black patients are disproportionally affected by asthma and also have poorer outcomes compared with white patients.
objectiveWe sought to determine associations between black and white patients and asthma-related health care use, accounting for complex relationships.
methodsThis study was completed as part of the National Heart, Lung, and Blood Institute's Severe Asthma Research Program, a prospective observational cohort. Between November 2012 and February 2015, it enrolled 579 participants 6 years and older with 1 year of observation time and complete data. Inverse probability of treatment weighting was used to balance racial groups with respect to community and family socioeconomic variables and environmental exposure variables. The primary outcome was emergency department (ED) use for asthma. Secondary outcomes included inhaled corticosteroid use, outpatient physician's office visits for asthma, and asthma-related hospitalization.
resultsBlack patients had greater odds of ED use over 1 year (odds ratio, 2.19; 95% CI, 1.43-3.35) but also differed in the majority (>50%) of baseline variables measured. After statistical balancing of the racial groups, the difference between black and white patients with respect to ED use no longer reached the level of significance. Instead, in secondary analyses black patients were less likely to see an outpatient physician for asthma management (adjusted odds ratio, 0.57; 95% CI, 0.38-0.85).
conclusionsThe disparity in ED use was eliminated after consideration of multiple variables. Social and environmental policies and interventions tailored to black populations with a high burden of asthma are critical to reduction (or elimination) of these disparities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.