Evidence map›Paper›PMID 30635064›Full record

ArticleTrials2019

Guided meditation as an adjunct to enhance postoperative recovery after cardiac surgery: study protocol for a prospective randomized controlled feasibility trial.

Senthil Packiasabapathy, Ammu T Susheela, Ariel Mueller, Melissa Patxot, Doris-Vanessa Gasangwa, Brian O'Gara, Shahzad Shaefi, Edward R Marcantonio, Gloria Y Yeh, Balachundhar Subramaniam

3 registry-linked trialsOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03198039 nacompletednot on this map

Guided Meditation as an Adjunct to Enhance Postoperative Recovery: A Feasibility Study

TypeinterventionalSponsorBeth Israel Deaconess Medical CenterRan2017 to 2020Enrolled29ConditionsFeasibility of a Meditation Program PerioperativelyArmsMeditation
NCT05295004 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Effect of Mindfulness Training Before Primary Total Joint Arthroplasty on Sleep Quality

TypeinterventionalSponsorColorado Joint ReplacementRan2022 to 2024Enrolled282ConditionsSleep Disturbance, ArthropathyArmsMindfulness Meditation Training
NCT05669066 nacompletednot on this map

The Effect of Mindful Meditation on Opioid Consumption in Patients Who Undergo Primary Total Hip and Knee Replacement

TypeinterventionalSponsorBeth Israel Deaconess Medical CenterRan2017 to 2021Enrolled29ConditionsArthropathy of Knee, Osteo Arthritis Knee, Osteonecrosis, MeditationArmsMindful meditation
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  8. Targets for Intervention? Preoperative Predictors of Postoperative Ileus After Colorectal Surgery in an Enhanced Recovery Protocol.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Senthil PackiasabapathyDepartment of Anesthesia, Critical Care and Pain Medicine, Indiana University School of Medicine, 340 W 10th St #6200, Indianapolis, IN, 46202, USA.
Ammu T SusheelaDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA, 02215, USA.
Ariel MuellerDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA, 02215, USA.
Melissa PatxotDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA, 02215, USA.
Doris-Vanessa GasangwaDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA, 02215, USA.
Brian O'GaraDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA, 02215, USA.
Shahzad ShaefiDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA, 02215, USA.
Edward R MarcantonioHarvard Medical School, 25 Shattuck St, Boston, MA, 02115, USA.
Gloria Y YehHarvard Medical School, 25 Shattuck St, Boston, MA, 02115, USA.
Balachundhar SubramaniamDepartment of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA, 02215, USA. bsubrama@bidmc.harvard.edu.ORCID http://orcid.org/0000-0001-6510-3885
Beth Israel Deaconess Medical Center · USIndiana University School of Medicine

Funding

Mid-Career Mentoring Award for Patient-Oriented Research in AgingK24AG035075 · NIA · BETH ISRAEL DEACONESS MEDICAL CENTER · PI MARCANTONIO, EDWARD R · 2010 to 2021
$1.9M
Mentoring and Patient-Oriented Research in Mind-Body ExerciseK24AT009465 · NCCIH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI GLORIA Y YEH · 2017 to 2026
$1.3M
NCCIH NIH HHS K24 AT009465NIA NIH HHS K24 AG035075
6 · The paper itself

Abstract

backgroundCardiac surgical procedures are associated with postoperative neurological complications such as cognitive decline and delirium, which can complicate recovery and impair quality of life. Perioperative depression and anxiety may be associated with increased mortality after cardiac surgeries. Surgical prehabilitation is an emerging concept that includes preoperative interventions to potentially reduce postoperative complications. While most current prehabilitation interventions focus on optimizing physical health, mind-body interventions are an area of growing interest. Preoperative mind-body interventions such as Isha Kriya meditation, may hold significant potential to improve postsurgical outcomes.

methodsThis is a prospective, randomized controlled feasibility trial. A total of 40 adult patients undergoing cardiac surgery will be randomized to one of three study groups. Participants randomized to either of the two intervention groups will receive meditative intervention: (1) commencing two weeks before surgery; or (2) commencing only from the day after surgery. Meditative intervention will last for four weeks after the surgery in these groups. Participants in the third control group will receive the current standard of care with no meditative intervention. All participants will undergo assessments using neurocognitive, sleep, depression, anxiety, and pain questionnaires at various time points in the perioperative period. Blood samples will be collected at baseline, preoperatively, and postoperatively to assess for inflammatory biomarkers. The primary aim of this trial is to assess the feasibility of implementing a perioperative meditative intervention program. Other objectives include studying the effect of meditation on postoperative pain, sleep, psychological wellbeing, cognitive function, and delirium. These will be used to calculate effect size to design future studies. DISCUSSION: This study serves as the first step towards understanding the feasibility of implementing a mind-body intervention as a prehabilitative intervention to improve postoperative surgical outcomes after cardiac surgery.

trial registrationClinicaltrials.gov, NCT03198039 . Registered on 23 June 2017.

Indexed as

AffectAnxietyBostonCardiac Surgical ProceduresCognitionDepressionFeasibility StudiesHealth StatusHumansMeditationMental HealthNeurocognitive DisordersNeuropsychological TestsPilot ProjectsPreoperative CareProspective StudiesCardiac surgeryDeliriumDepression, Anxiety, and Stress Scale (DASS-21)Isha KriyaMeditationMontreal Cognitive Assessment (MoCA)Patient-Reported Outcomes Measurement Information System (PROMIS) SurveysPittsburgh Sleep Quality Index (PSQI)Postoperative cognitive declinePrehabilitation

Identifiers

PMID30635064
PMCPMC6329114
OpenAlexW2913646300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.