Evidence map›Paper›PMID 30635012›Full record

SynthesisJournal of orthopaedic surgery and research2019

Risk factors associated with cardiac complication after total joint arthroplasty of the hip and knee: a systematic review.

Yassin Elsiwy, Ivana Jovanovic, Kenji Doma, Kaushik Hazratwala, Hayley Letson

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Journal of orthopaedic surgery and research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.

  1. Pooled it
  2. Effect of Comorbidities on Short-Term Postoperative Complications Following total Shoulder Arthroplasty: A TriNetX Study.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
    Article
  3. Article
  4. Article
  5. Article
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  7. Heart failure patients demonstrate excellent 1-year outcomes after total knee arthroplasty despite high healthcare utilization.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
  8. Article
  9. Article
  10. Short-term outcomes of outpatient total joint arthroplasty in morbidly obese patients.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yassin ElsiwyOrthopaedic Research Institute of Queensland, Townsville, QLD, Australia.
Ivana JovanovicOrthopaedic Research Institute of Queensland, Townsville, QLD, Australia.
Kenji DomaOrthopaedic Research Institute of Queensland, Townsville, QLD, Australia.
Kaushik HazratwalaOrthopaedic Research Institute of Queensland, Townsville, QLD, Australia.
Hayley LetsonCollege of Medicine and Dentistry, James Cook University, Townsville, QLD, Australia. Hayley.letson@jcu.edu.au.ORCID http://orcid.org/0000-0003-0135-134X
Sydney Orthopaedic Research Institute · AUJames Cook University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac complication represents a major cause of morbidity and mortality after total joint arthroplasty, thus necessitating investigation into the associated risks in total hip arthroplasty and total knee arthroplasty. There remains a lack of clarity for many risk factors in the current literature. The aim of this systematic review is to assess the most recent published literature and identify the risk factors associated with cardiac complication in total hip arthroplasty and total knee arthroplasty.

methodsScopus, PubMed, CINHAL, and Cochrane were searched to identify studies published since 2008 reporting on risk factors associated with cardiac complication in elective primary in total hip arthroplasty and total knee arthroplasty in patients ≥18 years old with osteoarthritis. Reported odds ratios, hazard ratios, and relative risk were the principal summary measures collected. The included studies were too heterogeneous to enable meta-analysis.

resultsFifteen studies were included in this systematic review. Increasing age and history of cardiac disease were found by most studies to be positively associated with risk of cardiac complication. There was no strong association found between obesity and cardiac complication. The evidence for other risk factors was less clear in the examined literature, although there is suggestive evidence for male gender and cerebrovascular disease increasing risk.

conclusionsIncreasing age and history of cardiac disease increases the risk of cardiac complication after total hip arthroplasty and total knee arthroplasty. Other risk factors commonly attributed to increased risk in non-cardiac surgery including hypertension and obesity require further evaluation in arthroplasty. SYSTEMATIC REVIEW REGISTRATION: A detailed protocol was published in the PROSPERO database (registration number CRD42018095887 ) for this systematic review.

Indexed as

Age FactorsArthroplasty, Replacement, HipArthroplasty, Replacement, KneeHeart DiseasesHumansOsteoarthritis, HipOsteoarthritis, KneePostoperative ComplicationsRisk FactorsArthroplastyCardiacComplicationRisk factorTHATKA

Identifiers

PMID30635012
PMCPMC6330438
OpenAlexW2914082710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.