Evidence map›Paper›PMID 30634710›Full record

ArticleMarine drugs2019

From Aggregates to Porous Three-Dimensional Scaffolds through a Mechanochemical Approach to Design Photosensitive Chitosan Derivatives.

Kseniia N Bardakova, Tatiana A Akopova, Alexander V Kurkov, Galina P Goncharuk, Denis V Butnaru, Vitaliy F Burdukovskii, Artem A Antoshin, Ivan A Farion, Tatiana M Zharikova, Anatoliy B Shekhter and 3 more

Abstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Mechanochemical Transformations of Polysaccharides: A Systematic Review.International journal of molecular sciences · 2022
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kseniia N BardakovaInstitute for Regenerative Medicine, Sechenov University, 8-2 Trubetskaya st., Moscow 119991, Russia. arie5@yandex.ru.ORCID 0000-0002-3942-5706
Tatiana A AkopovaEnikolopov Institute of Synthetic Polymer Materials, Russian Academy of Sciences, 70 Profsoyuznaya st., Moscow 117393, Russia. akopova@ispm.ru.
Alexander V KurkovInstitute for Regenerative Medicine, Sechenov University, 8-2 Trubetskaya st., Moscow 119991, Russia. a-kurkov@yandex.ru.ORCID 0000-0002-6258-3067
Galina P GoncharukEnikolopov Institute of Synthetic Polymer Materials, Russian Academy of Sciences, 70 Profsoyuznaya st., Moscow 117393, Russia. duna2011@yandex.ru.
Denis V ButnaruInstitute for Regenerative Medicine, Sechenov University, 8-2 Trubetskaya st., Moscow 119991, Russia. butnaru.dw@gmail.com.ORCID 0000-0003-2173-0566
Vitaliy F BurdukovskiiBaikal Institute of Nature Management, Siberian Branch of the Russian Academy of Sciences, 6 Sakhyanovoy st., Ulan-Ude 670047, Russia. burdvit@mail.ru.
Artem A AntoshinInstitute for Regenerative Medicine, Sechenov University, 8-2 Trubetskaya st., Moscow 119991, Russia. antoshin.art@gmail.com.ORCID 0000-0003-0575-0321
Ivan A FarionBaikal Institute of Nature Management, Siberian Branch of the Russian Academy of Sciences, 6 Sakhyanovoy st., Ulan-Ude 670047, Russia. fariv@mail.ru.ORCID 0000-0003-2723-6569
Tatiana M ZharikovaInstitute for Regenerative Medicine, Sechenov University, 8-2 Trubetskaya st., Moscow 119991, Russia. zharikova.tm@gmail.com.
Anatoliy B ShekhterInstitute for Regenerative Medicine, Sechenov University, 8-2 Trubetskaya st., Moscow 119991, Russia. a.shehter@yandex.ru.
Vladimir I YusupovInstitute of Photonic Technologies, Research center "Crystallography and Photonics", Russian Academy of Sciences, 2 Pionerskaya st., Troitsk, Moscow 108840, Russia. timashev.peter@gmail.com.ORCID 0000-0001-7773-2435
Peter S TimashevInstitute for Regenerative Medicine, Sechenov University, 8-2 Trubetskaya st., Moscow 119991, Russia. yury.rochev@nuigalway.ie.
Yury A RochevInstitute for Regenerative Medicine, Sechenov University, 8-2 Trubetskaya st., Moscow 119991, Russia. iouss@yandex.ru.

Funding

Ministry of Science and Higher Education within the State assignment FSRC «Crystallography and Photonics» RAS (wavelet analysis of samples)Russian academic excellence project '5-100' (in vivo and morphological studies, the development of a photosensitive composition)Russian Foundation for Basic Research 18-32-00222 (laser stereolithography of hydrogel matrices)Russian Science Foundation 15-15-00132 (formation of film and three-dimensional samples, their characterization)
6 · The paper itself

Abstract

The crustacean processing industry produces large quantities of waste by-products (up to 70%). Such wastes could be used as raw materials for producing chitosan, a polysaccharide with a unique set of biochemical properties. However, the preparation methods and the long-term stability of chitosan-based products limit their application in biomedicine. In this study, different scale structures, such as aggregates, photo-crosslinked films, and 3D scaffolds based on mechanochemically-modified chitosan derivatives, were successfully formed. Dynamic light scattering revealed that aggregation of chitosan derivatives becomes more pronounced with an increase in the number of hydrophobic substituents. Although the results of the mechanical testing revealed that the plasticity of photo-crosslinked films was 5⁻8% higher than that for the initial chitosan films, their tensile strength remained unchanged. Different types of polymer scaffolds, such as flexible and porous ones, were developed by laser stereolithography

Indexed as

Biocompatible MaterialsTissue EngineeringAnimalsCarbohydrate ConformationChitosanMaterials TestingPorosityRatsRats, WistarTensile StrengthTissue ScaffoldsBiocompatible MaterialsChitosanchitosanlaser stereolithographylong-term stabilitymechanochemical synthesisscaffoldtissue reaction

Identifiers

PMID30634710
PMCPMC6356335

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.