Evidence map›Paper›PMID 30634655›Full record

Trial reportNutrients2019

Exposure to Different Amounts of Dietary Gluten in Patients with Non-Celiac Gluten Sensitivity (NCGS): An Exploratory Study.

Leda Roncoroni, Karla A Bascuñán, Maurizio Vecchi, Luisa Doneda, Maria T Bardella, Vincenza Lombardo, Alice Scricciolo, Federica Branchi, Luca Elli

Abstract readClinical Trial
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Non-Celiac Gluten Sensitivity: An Update.Medicina (Kaunas, Lithuania) · 2021
    Review
  15. Observational
  16. Review
  17. Non-Celiac Gluten Sensitivity: A Review.Medicina (Kaunas, Lithuania) · 2019
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Leda RoncoroniCenter for Prevention and Diagnosis of Celiac Disease, Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20135 Milan, Italy. leda.roncoroni@unimi.it.
Karla A BascuñánCenter for Prevention and Diagnosis of Celiac Disease, Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20135 Milan, Italy. kbascunan@med.uchile.cl.ORCID 0000-0002-3759-2121
Maurizio VecchiDepartment of Pathophysiology and Transplantation, University of Milan, 20122 Milan, Italy. maurizio.vecchi@policlinico.mi.it.
Luisa DonedaDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, 20133 Milan, Italy. luisa.doneda@unimi.it.
Maria T BardellaCenter for Prevention and Diagnosis of Celiac Disease, Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20135 Milan, Italy. mariateresa.bardella@yahoo.com.
Vincenza LombardoCenter for Prevention and Diagnosis of Celiac Disease, Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20135 Milan, Italy. vicky.l@hotmail.it.
Alice ScriccioloCenter for Prevention and Diagnosis of Celiac Disease, Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20135 Milan, Italy. scricciolo.alice@gmail.com.
Federica BranchiCenter for Prevention and Diagnosis of Celiac Disease, Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20135 Milan, Italy. federica.branchi@gmail.com.ORCID 0000-0001-9217-8241
Luca ElliCenter for Prevention and Diagnosis of Celiac Disease, Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20135 Milan, Italy. dottorlucaelli@gmail.com.

Funding

Italian Ministry of Health and Lumbardy's Regional Government Authority (Ministero della Salute and Regione Lombardia) 2011-02348234
6 · The paper itself

Abstract

It is unclear whether patients with non-celiac gluten sensitivity (NCGS) can tolerate gluten. We have evaluated the changes of both gastrointestinal symptoms and quality of life for NCGS patients after the re-introduction of dietary gluten. Twenty-two NCGS patients reporting functional gastroenterological symptoms and on gluten-free diet (GFD) for the previous three weeks were exposed to incremental gluten-containing diets. Three groups were compared at baseline (immediately after 3-weeks on GFD) and immediately after the return of symptomatology: (i) a group tolerating a low-gluten diet (3.5 g gluten/day, week 1,

Indexed as

DietMalabsorption SyndromesAbdominal PainAdultCeliac DiseaseConstipationDiet, Gluten-FreeDyspepsiaFemaleGlutensHumansMaleMiddle AgedQuality of LifeGlutensgastrointestinal symptomsgluten-free dietgluten re-introductionnon-celiac gluten sensitivity

Identifiers

PMID30634655
PMCPMC6356445

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.