Evidence map›Paper›PMID 30634572›Full record

ArticleAnimals : an open access journal from MDPI2019

Dietary Verbascoside Influences Gut Morphology and the Expression of α-Transducin and α-Gustducin in the Small Intestine of Weaned Piglets Exposed to n-6 Polyunsaturated Fatty Acids-Induced Oxidative Stress.

Raffaella Rossi, Carlo Corino, Silvia Modina, Alessia Di Giancamillo

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Verbascoside-Rich Plant Extracts in Animal Nutrition.Antioxidants (Basel, Switzerland) · 2023
    Review
  3. Review
  4. Article
  5. Nutritional Regulation of Gut Barrier Integrity in Weaning Piglets.Animals : an open access journal from MDPI · 2019
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Raffaella RossiDepartment of Health, Animal Science and Food Safety, University of Milan, Via Celoria 10, 20133 Milan, Italy. raffaella.rossi@unimi.it.
Carlo CorinoDepartment of Health, Animal Science and Food Safety, University of Milan, Via Celoria 10, 20133 Milan, Italy. carlo.corino@unimi.it.ORCID 0000-0001-8146-0583
Silvia ModinaDepartment of Health, Animal Science and Food Safety, University of Milan, Via Celoria 10, 20133 Milan, Italy. silvia.modina@unimi.it.ORCID 0000-0002-2780-5971
Alessia Di GiancamilloDepartment of Health, Animal Science and Food Safety, University of Milan, Via Celoria 10, 20133 Milan, Italy. alessia.digiancamillo@unimi.it.ORCID 0000-0003-1674-3020
University of Milan · IT

Funding

Università degli Studi di Milano PSR2015-1716CDOME02_M
6 · The paper itself

Abstract

Reducing oxidative stress is an important goal in post-weaning piglets; previous studies have reported that verbascoside decreases oxidative stress in piglets. The effect of verbascoside on gut morphology and α-transducin and α-gustducin expression in weaned piglets fed high dosages of sunflower oil, inducing oxidative stress, was evaluated. A diet with 9% sunflower oil (T1), the same diet supplemented with 5 mg of verbascoside/kg feed (T2) and a diet containing starch (control-CTR) were employed. Histology, histometry, histochemistry, immunofluorescence and Western blot analyses were performed on the piglets' small intestine. In the T1 group, apical erosion was observed and villi height was lower than in other groups. The mucin profile was acidic in goblet cells of both the T1 and T2 groups. However, it was both neutral and acidic in the CTR group. Dietary treatments did not affect α-gustducin expression. Otherwise, the expression of α-transducin in the duodenum was lower (

Indexed as

gutpigletsverbascosideα-gustducinα-transducin

Identifiers

PMID30634572
PMCPMC6356580
OpenAlexW2909844426

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.