Evidence map›Paper›PMID 30634564›Full record

ArticleMolecules (Basel, Switzerland)2019

Moose and Caribou as Novel Sources of Functional Lipids: Fatty Acid Esters of Hydroxy Fatty Acids, Diglycerides and Monoacetyldiglycerides.

Thu Huong Pham, Natalia P Vidal, Charles F Manful, Tiffany A Fillier, Ryley P Pumphrey, Karen M Doody, Raymond H Thomas

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 49 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Thu Huong PhamSchool of Science and the Environment/Boreal Ecosystem Research Initiative, Grenfell Campus, Memorial University of Newfoundland, 20 University Drive, Corner Brook, NL A2H 5G4, Canada. tpham@grenfell.mun.ca.ORCID 0000-0002-1615-8916
Natalia P VidalSchool of Science and the Environment/Boreal Ecosystem Research Initiative, Grenfell Campus, Memorial University of Newfoundland, 20 University Drive, Corner Brook, NL A2H 5G4, Canada. nprietovidal@grenfell.mun.ca.ORCID 0000-0002-3527-1471
Charles F ManfulSchool of Science and the Environment/Boreal Ecosystem Research Initiative, Grenfell Campus, Memorial University of Newfoundland, 20 University Drive, Corner Brook, NL A2H 5G4, Canada. cfmanful@grenfell.mun.ca.
Tiffany A FillierSchool of Science and the Environment/Boreal Ecosystem Research Initiative, Grenfell Campus, Memorial University of Newfoundland, 20 University Drive, Corner Brook, NL A2H 5G4, Canada. tfillier@grenfell.mun.ca.
Ryley P PumphreySchool of Science and the Environment/Boreal Ecosystem Research Initiative, Grenfell Campus, Memorial University of Newfoundland, 20 University Drive, Corner Brook, NL A2H 5G4, Canada. rpp877@mun.ca.
Karen M DoodySchool of Science and the Environment/Boreal Ecosystem Research Initiative, Grenfell Campus, Memorial University of Newfoundland, 20 University Drive, Corner Brook, NL A2H 5G4, Canada. kdoody@grenfell.mun.ca.
Raymond H ThomasSchool of Science and the Environment/Boreal Ecosystem Research Initiative, Grenfell Campus, Memorial University of Newfoundland, 20 University Drive, Corner Brook, NL A2H 5G4, Canada. rthomas@grenfell.mun.ca.
Memorial University of Newfoundland · CA

Funding

Atlantic Canada Opportunities Agency 206869Natural Sciences and Engineering Research Council of Canada RGPIN-2016-04464Research and Development Corporation of Newfoundland and Labrador 5404-1815-101
6 · The paper itself

Abstract

Fatty acid esters of hydroxy fatty acids (FAHFA), diglycerides (DG) and monoacetyldiglycerides (MAcDG) are gaining interest as functional lipids in pharmaceuticals and functional food formulations for managing and treating metabolic or inflammatory diseases. Herein, we investigated whether the antler and/or meat of two Cervids (moose and caribou) are novel sources of FAHFA, DG and MAcDG. We observed FAHFA present in moose and caribou composed mainly of polyunsaturated families, and that the esterification occurred frequently at the C5-hydroxy fatty acid moiety, most noticeably arachidonic acid 5-hydroxyeicosatrienoic acid (ARA-5-HERA). Moose antler, caribou and moose meat also contained significant levels of both 1,2-DG and 1,3-DG lipids. The 1,3-DG molecular species consisted mainly of 16:0/18:1, 18:0/16:0, and 18:0/18:1. On the other hand, major 1,2-DG species consisted of DG 18:0/18:0, 16:0/16:0 and 18:1/18:1 molecular species with higher levels in the antler compared to the meat. The molecular species composition of MAcDG was very simple and consisted of 14:2/18:2/2:0, 16:0/18:2/2:0, 16:0/18:1/2:0 and 18:0/18:1/2:0 with the first species 14:2/18:2/2:0 predominating in the tip of moose antlers. Increasing access to and knowledge of the presence of these functional lipids in foods will enhance their intake in the diet with potential implications in improving personal and population health.

Indexed as

AnimalsAntlersDeerDiglyceridesDrug IndustryEstersFatty AcidsFunctional FoodLipidsMeatDiglyceridesEstersFatty AcidsLipidsdiglyceridesfatty acid esters of hydroxy fatty acidsfunctional foodsfunctional lipidsmonoacetyldiglyceridesregioisomers

Identifiers

PMID30634564
PMCPMC6359430
OpenAlexW2910955798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.