Evidence map›Paper›PMID 30634554›Full record

ReviewViruses2019

Friend or Foe: The Role of the Cytoskeleton in Influenza A Virus Assembly.

Sukhmani Bedi, Akira Ono

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 40 citations in OpenAlex.

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  16. Journal of virology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sukhmani BediDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, MI 48109, USA. sukhbedi@umich.edu.
Akira OnoDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, MI 48109, USA. akiraono@umich.edu.ORCID 0000-0001-7841-851X
University of Michigan · US

Funding

Mechanisms that determine subcellular sites of HIV-1 assemblyR37AI071727 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Akira Ono · 2017 to 2026
$6.2M
Mechanisms that determine subcellular sites of HIV-1 assemblyR01AI071727 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ONO, AKIRA · 2007 to 2016
$3.6M
Cell-specific restriction of influenza A virus assemblyR21AI143276 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ONO, AKIRA · 2019 to 2020
$416k
National Institute of Allergy and Infectious Diseases R01AI071727National Institute of Allergy and Infectious Diseases R21AI143276NIAID NIH HHS R01 AI071727NIAID NIH HHS R21 AI143276NIAID NIH HHS R37 AI071727
6 · The paper itself

Abstract

Influenza A Virus (IAV) is a respiratory virus that causes seasonal outbreaks annually and pandemics occasionally. The main targets of the virus are epithelial cells in the respiratory tract. Like many other viruses, IAV employs the host cell's machinery to enter cells, synthesize new genomes and viral proteins, and assemble new virus particles. The cytoskeletal system is a major cellular machinery, which IAV exploits for its entry to and exit from the cell. However, in some cases, the cytoskeleton has a negative impact on efficient IAV growth. In this review, we highlight the role of cytoskeletal elements in cellular processes that are utilized by IAV in the host cell. We further provide an in-depth summary of the current literature on the roles the cytoskeleton plays in regulating specific steps during the assembly of progeny IAV particles.

Indexed as

Host-Pathogen InteractionsVirus AssemblyActinsCell LineCytoskeletonEpithelial CellsHumansInfluenza A virusMicrotubulesActinsactincytoskeletoninfluenzamicrotubulesvirus assembly

Identifiers

PMID30634554
PMCPMC6356976
OpenAlexW2908986972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.