Evidence map›Paper›PMID 30634409›Full record

ArticleJournal of clinical medicine2019

Multispectral Optoacoustic Tomography: Intra- and Interobserver Variability Using a Clinical Hybrid Approach.

Anne Helfen, Max Masthoff, Jing Claussen, Mirjam Gerwing, Walter Heindel, Vasilis Ntziachristos, Michel Eisenblätter, Michael Köhler, Moritz Wildgruber

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Optoacoustic muscle imaging.Journal of neuromuscular diseases · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Molecular imaging of psoriatic arthritis.Current opinion in rheumatology · 2025
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Regional motion correction forBiomedical optics express · 2021
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anne HelfenInstitute of Clinical Radiology, Medical Faculty, University of Muenster, and University Hospital Muenster, 48149 Muenster, Germany. anne.helfen@ukmuenster.de.
Max MasthoffInstitute of Clinical Radiology, Medical Faculty, University of Muenster, and University Hospital Muenster, 48149 Muenster, Germany. max.masthoff@ukmuenster.de.
Jing ClausseniThera Medical, 81379 Munich, Germany. jing.claussen@ithera-medical.com.
Mirjam GerwingInstitute of Clinical Radiology, Medical Faculty, University of Muenster, and University Hospital Muenster, 48149 Muenster, Germany. Mirjam.Gerwing@ukmuenster.de.
Walter HeindelInstitute of Clinical Radiology, Medical Faculty, University of Muenster, and University Hospital Muenster, 48149 Muenster, Germany. heindel@uni-muenster.de.
Vasilis NtziachristosInstitute for Biological and Medical Imaging, Technical University of Munich, 81675 Munich, Germany. vntziachristos@gmail.com.
Michel EisenblätterInstitute of Clinical Radiology, Medical Faculty, University of Muenster, and University Hospital Muenster, 48149 Muenster, Germany. eisenblaetter@uni-muenster.de.
Michael KöhlerInstitute of Clinical Radiology, Medical Faculty, University of Muenster, and University Hospital Muenster, 48149 Muenster, Germany. michael.koehler@ukmuenster.de.
Moritz WildgruberInstitute of Clinical Radiology, Medical Faculty, University of Muenster, and University Hospital Muenster, 48149 Muenster, Germany. moritz.wildgruber@ukmuenster.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multispectral optoacoustic tomography (MSOT) represents a new imaging approach revealing functional tissue information without extrinsic contrast agents. Using a clinical combined ultrasound (US)/MSOT device, we investigated the interindividual robustness and impact of intra- and interobserver variability of MSOT values in soft tissue (muscle and subcutaneous fat) of healthy volunteers. Semiquantitative MSOT values for deoxygenated (Hb), oxygenated (HbO₂) and total hemoglobin (HbT), as well as oxygen saturation (sO₂), were calculated for both forearms in transversal and longitudinal probe orientation (

Indexed as

interrater variabilityintrarater variabilitymultispectral optoacoustic tomographyphotoacoustic imagingreproducibility

Identifiers

PMID30634409
PMCPMC6352009

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.