Evidence map›Paper›PMID 30634402›Full record

ArticleVeterinary sciences2019

Deregulation of VEGFR-2 and PDGFR Expression and Microvascular Density in a Triple-Negative Model of Canine Malignant Mammary Tumors with Lymph Node or Lung Metastasis.

Denner Santos Dos Anjos, Aline Fernandes Vital, Patrícia de Faria Lainetti, Antonio Fernando Leis-Filho, Fabiola Dalmolin, Fabiana Elias, Sabryna Gouveia Calazans, Carlos Eduardo Fonseca-Alves

Open access · goldAbstract read
In one paragraph

Article in Veterinary sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Denner Santos Dos AnjosVeterinary Science Graduate Program, University of Franca (UNIFRAN), Franca 14404-600, Brazil. dennerbiovet@hotmail.com.ORCID 0000-0003-1804-475X
Aline Fernandes VitalVeterinary Science Graduate Program, University of Franca (UNIFRAN), Franca 14404-600, Brazil. alinefernandesvital@hotmail.com.
Patrícia de Faria LainettiDepartment of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, São Paulo State University-UNESP, Botucatu 18618-681, Brazil. patylainetti@hotmail.com.
Antonio Fernando Leis-FilhoDepartment of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, São Paulo State University-UNESP, Botucatu 18618-681, Brazil. nandoleis@hotmail.com.
Fabiola DalmolinSuperintendencia Unidade Hospitalar Veterinaria Universitaria, Federal University of the Fronteira Sul, Realeza 85770-000, Brazil. fabiola.dalmolin@uffs.edu.br.
Fabiana EliasSuperintendencia Unidade Hospitalar Veterinaria Universitaria, Federal University of the Fronteira Sul, Realeza 85770-000, Brazil. elias.fabiana@gmail.com.
Sabryna Gouveia CalazansVeterinary Science Graduate Program, University of Franca (UNIFRAN), Franca 14404-600, Brazil. sabryna.calazans@gmail.com.
Carlos Eduardo Fonseca-AlvesDepartment of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, São Paulo State University-UNESP, Botucatu 18618-681, Brazil. carlos.e.alves@unesp.br.ORCID 0000-0002-6702-6139
Universidade de Franca · BRUniversidade Estadual Paulista (Unesp) · BRUniversidade Federal da Fronteira Sul · BR

Funding

Sao Paulo Research Foundation - FAPESP 2015/02798-5
6 · The paper itself

Abstract

Canine mammary tumors (CMT) represent the most common cancer in noncastrated female dogs. Interestingly, triple-negative tumors are the most common molecular subtype in female dogs. In this study, we proposed to evaluate the expression of vascular endothelial growth factor receptor 2 (VEGFR-2), Platelet-derived growth factor receptor (PDGFR), and microvascular density (MVD) in a group of metastatic and nonmetastatic triple-negative CMT and compare the expression based on clinical parameters. Twenty-six female dogs with triple-negative mammary tumors were divided into three groups: nonmetastatic tumors (NMT) (

Indexed as

angiogenesismammary neoplasmmetastasis

Identifiers

PMID30634402
PMCPMC6466043
OpenAlexW2904270500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.