Evidence map›Paper›PMID 30633907›Full record

ArticleCell2019

Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma.

Moshe Sade-Feldman, Keren Yizhak, Stacey L Bjorgaard, John P Ray, Carl G de Boer, Russell W Jenkins, David J Lieb, Jonathan H Chen, Dennie T Frederick, Michal Barzily-Rokni and 25 more

Abstract readPublished Erratum
In one paragraph

Article in Cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 180 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
180citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

180 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Systematic review and meta-analysis efficacy and safety of immune checkpoint inhibitors in advanced melanoma patients with anti-PD-1 progression: a systematic review and meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2021
    Pooled it
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120 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

35 authors.

Moshe Sade-Feldman
Keren Yizhak
Stacey L Bjorgaard
John P Ray
Carl G de Boer
Russell W Jenkins
David J Lieb
Jonathan H Chen
Dennie T Frederick
Michal Barzily-Rokni
Samuel S Freeman
Alexandre Reuben
Paul J Hoover
Alexandra-Chloé Villani
Elena Ivanova
Andrew Portell
Patrick H Lizotte
Amir R Aref
Jean-Pierre Eliane
Marc R Hammond
Hans Vitzthum
Shauna M Blackmon
Bo Li
Vancheswaran Gopalakrishnan
Sangeetha M Reddy
Zachary A Cooper
Cloud P Paweletz
David A Barbie
Anat Stemmer-Rachamimov
Keith T Flaherty
Jennifer A Wargo
Genevieve M Boland
Ryan J Sullivan
Gad Getz
Nir Hacohen

Funding

Training Program in Bioinformatics and Integrative GenomicsT32HG002295 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Peter J Park · 2001 to 2026
$15.8M
Project 2U54CA224068 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI CORCORAN, RYAN BRUCE, FLAHERTY, KEITH T · 2017 to 2021
$6.3M
(PQ3) The role of damaged DNA in inter-individual variation of tumor immunityR01CA208756 · NCI · BROAD INSTITUTE, INC. · PI HACOHEN, NIR · 2016 to 2020
$2.6M
Cancer Immunology Training GrantT32CA207021 · NCI · DANA-FARBER CANCER INST · PI WUCHERPFENNIG, KAI W · 2016 to 2020
$2.4M
NCI NIH HHS R01 CA208756NCI NIH HHS T32 CA207021NCI NIH HHS U54 CA224068NHGRI NIH HHS T32 HG002295
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID30633907
PMCPMC6647017

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.