Evidence map›Paper›PMID 30633891›Full record

Trial reportAmerican journal of ophthalmology2019

Spectacle Adherence Among Four-Year-Old Children in the Infant Aphakia Treatment Study.

Scott R Lambert, Lindreth DuBois, George Cotsonis, E Eugenie Hartmann, Carolyn Drews-Botsch, Infant Aphakia Treatment Study Group

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in American journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00212134 (Infant Aphakia Treatment Study), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00212134 nacompletednot on this map

Infant Aphakia Treatment Study (IATS)

TypeinterventionalSponsorStanford UniversityRan2004 to 2020Enrolled114ConditionsCongenital CataractArmsContact lens correction of aphakia, Intraocular lens implantation
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. What we have learned from the Infant Aphakia Treatment Study: The 49th Annual Frank D. Costenbader Lecture.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2023
    Review
  4. Article
  5. Rate of ocular trauma in children operated on for unilateral cataract in infancy-data from the Infant Aphakia Treatment Study.Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus · 2020
    Article
  6. Review
  7. Update on pediatric cataract surgery.Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Scott R LambertDepartment of Ophthalmology, Stanford University School of Medicine, Stanford, California, USA. Electronic address: Lambert7@stanford.edu.
Lindreth DuBoisDepartment of Ophthalmology, Emory University, Atlanta, Georgia, USA.
George CotsonisDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
E Eugenie HartmannDepartment of Ophthalmology, Emory University, Atlanta, Georgia, USA.
Carolyn Drews-BotschDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Infant Aphakia Treatment Study Group

Funding

Infant Aphakia Treatment StudyU10EY013272 · NEI · EMORY UNIVERSITY · PI LAMBERT, SCOTT R · 2004 to 2014
$8.1M
Stanford Vision Research CoreP30EY026877 · NEI · STANFORD UNIVERSITY · PI Jeffrey L Goldberg · 2017 to 2026
$8.0M
Coordinating Center for Infant Aphakia Treatment Study (IATS)U10EY013287 · NEI · EMORY UNIVERSITY · PI LONG, QI · 2004 to 2014
$5.8M
Infant Aphakia Treatment Study-Clinical CentersUG1EY025553 · NEI · EMORY UNIVERSITY · PI DREWS-BOTSCH, CAROLYN DAWSON · 2015 to 2018
$933k
Coordinating Center for Infant Aphakia Treatment Study (IATS)UG1EY013287 · NEI · EMORY UNIVERSITY · PI NIZAM, AZHAR · 2015 to 2018
$917k
Infant Aphakia Treatment Study-Chairman's GrantUG1EY013272 · NEI · STANFORD UNIVERSITY · PI LAMBERT, SCOTT R · 2015 to 2018
$639k
NEI NIH HHS P30 EY026877NEI NIH HHS U10 EY013272NEI NIH HHS U10 EY013287NEI NIH HHS UG1 EY013272NEI NIH HHS UG1 EY013287NEI NIH HHS UG1 EY025553
6 · The paper itself

Abstract

purposeTo evaluate spectacle adherence with impact-resistant lenses among 4-year-old children after unilateral cataract surgery in the Infant Aphakia Treatment Study.

designRetrospective cohort analysis of randomized clinical trial data.

methodsSetting: Multicenter. PATIENTS: One hundred and fourteen children randomized to contact lens correction or intraocular lens implantation following unilateral cataract surgery during infancy.

interventionOne-week diaries completed annually and retrospective telephone interviews conducted every 3 months to age 5 years to assess spectacle adherence with impact-resistant lenses. Visual acuity was assessed by a traveling examiner at age 4.5 years.

main outcome measuresSpectacle adherence between ages 4 and 5 years.

resultsChildren with 20/40 or better vision in their treated eye were more likely to wear spectacles ≥80% of their waking hours than children with vision worse than 20/40 (66% vs 42%, P = .034). Reported adherence to spectacle wear correlated with reported patching (r = 0.30, P = .002). Spectacle adherence did not correlate with sex, type of healthcare insurance, or the refractive error in the treated or fellow eye. Seven patients with reduced vision in their treated eye reported <10% spectacle adherence.

conclusionsThese results confirm that it is possible to achieve high levels of spectacle adherence among 4-year-old children after unilateral cataract surgery during infancy. However, children with vision worse than 20/40 in their worse eye, who needed eye protection the most, had the worst adherence.

Indexed as

Aphakia, PostcataractCataractCataract ExtractionChild, PreschoolContact LensesEyeglassesFemaleHumansLens Implantation, IntraocularMalePatient ComplianceProsthesis FittingRefraction, OcularRefractive ErrorsRetrospective StudiesSurveys and Questionnaires

Identifiers

PMID30633891
PMCPMC6445735

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.