SynthesisHuman vaccines & immunotherapeutics2019
HPV vaccination in a context of public mistrust and uncertainty: a systematic literature review of determinants of HPV vaccine hesitancy in Europe.
Synthesis in Human vaccines & immunotherapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 186 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PREVENT: Practice-based Approaches to Promote HPV Vaccination in the Safety Net - BootCamp Translation
PREVENT: Practice-based Approaches to Promote HPV Vaccination in the Safety Net - Pilot Trial
PREVENT: Practice-based Approaches to Promote HPV Vaccination in the Safety Net - Randomized Controlled Trial (RCT)
Who cites it
186 citing papers in PubMed, 11 syntheses or guidelines pooled it, 303 citations in OpenAlex.
- Effects of human papillomavirus (HPV) vaccination programmes on community rates of HPV-related disease and harms from vaccination.The Cochrane database of systematic reviews · 2025Pooled it
- Human papillomavirus (HPV) vaccination for the prevention of cervical cancer and other HPV-related diseases: a network meta-analysis.The Cochrane database of systematic reviews · 2025Pooled it
- Factors that influence caregivers' and adolescents' views and practices regarding human papillomavirus (HPV) vaccination for adolescents: a qualitative evidence synthesis.The Cochrane database of systematic reviews · 2025Pooled it
- The structural and organizational aspects of human papillomavirus vaccine affecting immunization coverage in Europe: a systematic review.BMC public health · 2025Pooled it
- Global parental acceptance, attitudes, and knowledge regarding human papillomavirus vaccinations for their children: a systematic literature review and meta-analysis.BMC women's health · 2024Pooled it
- Safety of COVID-19 Pfizer-BioNtech (BNT162b2) mRNA vaccination in adolescents aged 12-17 years: A systematic review and meta-analysis.Human vaccines & immunotherapeutics · 2022Pooled it
- Overcoming COVID-19 vaccine hesitancy among ethnic minorities: A systematic review of UK studies.Vaccine · 2022Pooled it
- Multi-perspectives systematic review on the applications of sentiment analysis for vaccine hesitancy.Computers in biology and medicine · 2021Pooled it
- Understanding the determinants of vaccine hesitancy and vaccine confidence among adolescents: a systematic review.Human vaccines & immunotherapeutics · 2021Pooled it
- Vaccination for Human Papillomavirus: an historic and bibliometric study.Human vaccines & immunotherapeutics · 2021Pooled it
- Cognitions and behaviours of general practitioners in France regarding HPV vaccination: A theory-based systematic review.Preventive medicine · 2021Pooled it
- AI Chatbot Use for Human Papillomavirus Vaccine Literacy in Japan: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Web-Based Video Intervention and Associated Factors for the Uptake of the Catch-Up Human Papillomavirus Vaccination in Japan: Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
- Can physicians and schools mitigate social inequalities in human papillomavirus vaccine awareness, uptake and vaccination intention among adolescents? A cross-sectional study, France, 2021 to 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2023Trial
- Trial
- The syndemic nexus: How vaccine hesitancy and COVID-19 interact to influence vaccine uptake among university students.Human vaccines & immunotherapeutics · 2026Article
- Determinants of HPV vaccination acceptance among young adult women in Japan's catch-up generation: A cross-sectional study.Human vaccines & immunotherapeutics · 2026Article
- School nurses' perceptions of providing the HPV vaccine to adolescents in undervaccinated communities in Stockholm: A qualitative study.Human vaccines & immunotherapeutics · 2026Article
- Addressing HPV vaccine hesitancy and misinformation in India through public health communication strategies.Human vaccines & immunotherapeutics · 2026Article
- Knowledge, Attitudes, and Perceptions of HPV Vaccination for Adolescents with Intellectual Disabilities: A Systematic Review.Vaccines · 2026Review
126 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 8 institutions in 6 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Europe is increasingly described as the region in the world with the least confidence in vaccination, and particularly in the safety of vaccines. The aim of this systematic literature review was to gather and summarise all peer-reviewed and grey literature published about determinants of Human Papillomavirus (HPV) vaccine hesitancy in Europe. Ten thematic categories were identified across the 103 articles which were included in the review. Participants from European studies most commonly reported issues with the quantity and quality of information available about HPV vaccination; followed by concerns about potential side effects of the vaccine; and mistrust of health authorities, healthcare workers, and new vaccines. Comparative analyses indicated that confidence determinants differed by country and population groups. This evidence supports the need to develop context-specific interventions to improve confidence in HPV vaccination and design community engagement strategies aiming to build public trust.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.