ArticleThe British journal of radiology2019
MRI-based assessment and characterization of epicardial and paracardial fat depots in the context of impaired glucose metabolism and subclinical left-ventricular alterations.
Article in The British journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 44 citations in OpenAlex.
- Mediastinal adipose tissue as an active player in cardiovascular disease: a multimodality imaging narrative review.Quantitative imaging in medicine and surgery · 2026Review
- Heart matters: How glucose- and lipid-modulating drugs remodel epicardial adipose tissue accumulation, inflammatory patterns and browning.Diabetes, obesity & metabolism · 2026Review
- Associations between adrenal gland volume and adipose tissue compartments - a whole body MRI study.Nutrition & metabolism · 2024Article
- Role of epicardial adipose tissue in diabetic cardiomyopathy through the lens of cardiovascular magnetic resonance imaging - a narrative review.Therapeutic advances in endocrinology and metabolism · 2024Review
- Targeting epicardial adipose tissue: A potential therapeutic strategy for heart failure with preserved ejection fraction with type 2 diabetes mellitus.World journal of diabetes · 2023Review
- Epicardial Adipose Tissue: A Piece of The Puzzle in Pediatric Hypertension.Journal of clinical medicine · 2023Article
- Pre-diabetes is associated with attenuation rather than volume of epicardial adipose tissue on computed tomography.Scientific reports · 2023Article
- Epicardial Adipose Tissue as an Independent Cardiometabolic Risk Factor for Coronary Artery Disease.Cureus · 2022Review
- Deep-Learning Segmentation of Epicardial Adipose Tissue Using Four-Chamber Cardiac Magnetic Resonance Imaging.Diagnostics (Basel, Switzerland) · 2022Article
- Epicardial Adipose Tissue and Cardiovascular Risk Assessment in Ultra-Marathon Runners: A Pilot Study.International journal of environmental research and public health · 2021Article
- Association of antecedent cardiovascular risk factor levels and trajectories with cardiovascular magnetic resonance-derived cardiac function and structure.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021Article
- Automated Quality-Controlled Cardiovascular Magnetic Resonance Pericardial Fat Quantification Using a Convolutional Neural Network in the UK Biobank.Frontiers in cardiovascular medicine · 2021Article
- Pericardial fat and its influence on cardiac diastolic function.Cardiovascular diabetology · 2020Article
- Cardiac MRI measurements of pericardial adipose tissue volumes in patients on in-centre nocturnal hemodialysis.Journal of nephrology · 2020Article
- Epicardial adipose tissue: an emerging biomarker of cardiovascular complications in type 2 diabetes?Therapeutic advances in endocrinology and metabolism · 2020Article
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Authors and funding
11 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objective: To analyze the associations between epicardial and paracardial fat and impaired glucose tolerance as well as left ventricular (LV) alterations.
methods: 400 subjects underwent 3 T MRI and fat depots were delineated in the four chamber-view of the steady-state free precession cine sequence (repetition time: 29.97 ms; echo time 1.46 ms). LV parameters were also derived from MRI. Oral glucose tolerance tests were performed.
results: Epi- and paracardial fat was derived in 372 (93%) subjects (220 healthy controls, 100 persons with prediabetes, 52 with diabetes). Epi- and paracardial fat increased from normal glucose tolerance (NGT) to prediabetes and diabetes (7.7 vs 9.2 vs 10.3 cm
conclusion: Although epicardial and paracardial fat are increased in prediabetes and diabetes, the association is mostly confounded by VAT. Epicardial fat is independently associated with subclinical LV impairment in subjects without known cardiovascular disease. ADVANCES IN KNOWLEDGE:: This study contributes to the picture of epicardial fat as a pathogenic local fat depot that is independently associated with MR-derived markers of left ventricular alterations.
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