Evidence map›Paper›PMID 30632990›Full record

ArticleAnnals of surgery2020

Multi-institution Evaluation of Adherence to Comprehensive Postoperative VTE Chemoprophylaxis.

Anthony D Yang, Daniel Brock Hewitt, Eddie Blay, Lindsey J Kreutzer, Christopher M Quinn, Kimberly A Cradock, Vivek Prachand, Karl Y Bilimoria, Illinois Surgical Quality Improvement Collaborative (ISQIC)

Abstract readMulticenter Study
In one paragraph

Article in Annals of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anthony D YangIllinois Surgical Quality Improvement Collaborative (ISQIC), Chicago, IL.
Daniel Brock HewittIllinois Surgical Quality Improvement Collaborative (ISQIC), Chicago, IL.
Eddie BlayIllinois Surgical Quality Improvement Collaborative (ISQIC), Chicago, IL.
Lindsey J KreutzerIllinois Surgical Quality Improvement Collaborative (ISQIC), Chicago, IL.
Christopher M QuinnIllinois Surgical Quality Improvement Collaborative (ISQIC), Chicago, IL.
Kimberly A CradockIllinois Surgical Quality Improvement Collaborative (ISQIC), Chicago, IL.
Vivek PrachandIllinois Surgical Quality Improvement Collaborative (ISQIC), Chicago, IL.
Karl Y BilimoriaIllinois Surgical Quality Improvement Collaborative (ISQIC), Chicago, IL.
Illinois Surgical Quality Improvement Collaborative (ISQIC)

Funding

Vascular Surgery Scientist Training ProgramT32HL094293 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ESKANDARI, MARK K · 2009 to 2023
$4.0M
Evaluating the Implementation of a Multi-Component Quality CollaborativeR01HS024516 · AHRQ · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BILIMORIA, KARL Y · 2016 to 2020
$1.2M
Tailored Adaptation of the AHRQ VTE QI Guide to Local Hospital Context.K08HL145139 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI YANG, ANTHONY D. · 2019 to 2023
$800k
AHRQ HHS R01 HS024516AHRQ HHS T32 HS000078NHLBI NIH HHS K08 HL145139NHLBI NIH HHS T32 HL094293
6 · The paper itself

Abstract

objectivesThe aims of this study were to: (1) measure the rate of failure to provide defect-free postoperative venous thromboembolism (VTE) chemoprophylaxis, (2) identify reasons for failure to provide defect-free VTE chemoprophylaxis, and (3) examine patient- and hospital-level factors associated with failure. SUMMARY BACKGROUND DATA: Current VTE quality measures are inadequate. VTE outcome measures are invalidated for interhospital comparison by surveillance bias. VTE process measures (e.g., SCIP-VTE-2) do not comprehensively capture failures throughout patients' entire hospitalization.

methodsWe examined adherence to a novel VTE chemoprophylaxis process measure in patients who underwent colectomies over 18 months at 36 hospitals in a statewide surgical collaborative. This measure assessed comprehensive VTE chemoprophylaxis during each patient's entire hospitalization, including reasons why chemoprophylaxis was not given. Associations of patient and hospital characteristics with measure failure were examined.

resultsThe SCIP-VTE-2 hospital-level quality measure identified failures of VTE chemoprophylaxis in 0% to 3% of patients. Conversely, the novel measure unmasked failure to provide defect-free chemoprophylaxis in 18% (736/4086) of colectomies. Reasons for failure included medication not ordered (30.4%), patient refusal (30.3%), incorrect dosage/frequency (8.2%), and patient off-unit (3.4%). Patients were less likely to fail the chemoprophylaxis process measure if treated at nonsafety net hospitals (OR 0.62, 95% CI 0.39-0.99, P = 0.045) or Magnet designated hospitals (OR 0.45, 95% CI 0.29-0.71, P = 0.001).

conclusionsIn contrast to SCIP-VTE-2, our novel quality measure unmasked VTE chemoprophylaxis failures in 18% of colectomies. Most failures were due to patient refusals or ordering errors. Hospitals should focus improvement efforts on ensuring patients receive VTE prophylaxis throughout their entire hospitalization.

Indexed as

Guideline AdherenceAdultAgedAnticoagulantsChemopreventionColectomyCross-Sectional StudiesFemaleHospitalsHumansIncidenceMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk AssessmentAnticoagulants

Identifiers

PMID30632990
PMCPMC6904538

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.