Evidence map›Paper›PMID 30632621›Full record

ArticleJournal of fish diseases2019

Exophiala angulospora infection in hatchery-reared lumpfish (Cyclopterus lumpus) broodstock.

Marcia Saraiva, Max J Beckmann, Sara Pflaum, Marianne Pearson, Daniel Carcajona, James W Treasurer, Pieter van West

Open access · hybridAbstract read
In one paragraph

Article in Journal of fish diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. SystemicFrontiers in veterinary science · 2023
    Article
  3. Phaeohyphomycosis due toPathogens (Basel, Switzerland) · 2022
    Article
  4. Species Diversity, Distribution, and Phylogeny ofJournal of fungi (Basel, Switzerland) · 2022
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Marcia SaraivaAberdeen Oomycete Laboratory, International Centre for Aquaculture Research and Development, Institute of Medical Sciences, Foresterhill, Aberdeen, UK.
Max J BeckmannAberdeen Oomycete Laboratory, International Centre for Aquaculture Research and Development, Institute of Medical Sciences, Foresterhill, Aberdeen, UK.
Sara PflaumFish Vet Group, Inverness, UK.
Marianne PearsonFish Vet Group, Inverness, UK.
Daniel CarcajonaFAI Aquaculture, Ardtoe Marine Research Facility, Acharacle, UK.
James W TreasurerFAI Aquaculture, Ardtoe Marine Research Facility, Acharacle, UK.ORCID https://orcid.org/0000-0002-3447-9449
Pieter van WestAberdeen Oomycete Laboratory, International Centre for Aquaculture Research and Development, Institute of Medical Sciences, Foresterhill, Aberdeen, UK.ORCID https://orcid.org/0000-0002-0767-6017
University of Aberdeen · GBMarine Scotland · GBSeafish · GB

Funding

Biotechnology and Biological Sciences Research Council BB/M026566/1Biotechnology and Biological Sciences Research Council BB/P020224/1Natural Environment Research Council NE/P007570/1University of Aberdeen
6 · The paper itself

Abstract

Samples from moribund lumpfish were collected in a marine hatchery in Scotland in 2015. Black nodules were noted on the skin, and gills and fungal hyphae were extensively distributed in musculature and internal organs. Multifocal chronic inflammatory lesions displaced structures in all affected organs. Mortalities commenced on completion of spawning in May and were evenly distributed over the second year in the temperature range 11-15°C. The main systemic infection causing agent was initially identified based on morphological characteristics as an Exophiala species. Ribosomal DNA (rDNA) ITS regions of the isolates were subsequently sequenced confirming the isolates belonged to Exophiala genus. All isolates fell in a single phylogenetic cluster, which is represented by Exophiala angulospora. Fish were treated with either formalin or Bronopol or a combination of both, but there was no effect on the pattern or numbers of mortalities. Isolates were also tested against three different concentrations of Latrunculin A, Amphotericin B and Itraconazole with no success. It is of utmost importance to increase the knowledge on pathogen-host interactions to successfully develop sustainable control methods.

Indexed as

PerciformesAnimalsAntifungal AgentsAnti-Infective AgentsAquacultureDNA, RibosomalExophialaFish DiseasesPhaeohyphomycosisPhylogenyScotlandAntifungal AgentsAnti-Infective AgentsDNA, Ribosomalcleaner fishCyclopterus lumpusExophiala angulosporaFunguslumpfish

Identifiers

PMID30632621
PMCPMC6378594
OpenAlexW2904502592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.