Evidence map›Paper›PMID 30632164›Full record

ArticleThe Journal of pathology2019

TRPV4 is involved in levonorgestrel-induced reduction in oviduct ciliary beating.

Cheng Li, Yan-Ting Wu, Qian Zhu, Hui-Yu Zhang, Zhen Huang, Duo Zhang, Hang Qi, Gui-Ling Liang, Xiao-Qing He, Xiao-Feng Wang and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Physiological Cooperation between Aquaporin 5 and TRPV4.International journal of molecular sciences · 2022
    Review
  7. Review
  8. Article
  9. Frontiers in cell and developmental biology · 2021
    Article
  10. Review
  11. Roles of steroid hormones in oviductal functionReproduction (Cambridge, England) · 2020
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Cheng LiInternational Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Yan-Ting WuInternational Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Qian ZhuInternational Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Hui-Yu ZhangInternational Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Zhen HuangInternational Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Duo ZhangInternational Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Hang QiInternational Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Gui-Ling LiangInternational Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Xiao-Qing HeInternational Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Xiao-Feng WangInternational Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Xue TangInternational Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
He-Feng HuangInternational Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
Jian ZhangInternational Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.ORCID 0000-0002-7381-4940
Shanghai Jiao Tong University · CNShanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies revealed the increasing risk of tubal pregnancy following failure of levonorgestrel (LNG)-induced emergency contraception, which was attributed to the reduced ciliary motility in response to LNG. However, understanding of the mechanism of LNG-induced reduction in the ciliary beat frequency (CBF) is limited. The transient receptor potential vanilloid (TRPV) 4 channel is located widely in the female reproductive tract and generates an influx of Ca

Indexed as

AnimalsCalciumCell LineCiliaContraception, PostcoitalContraceptive Agents, HormonalContraceptive EffectivenessContraceptives, PostcoitalDown-RegulationEpithelial CellsFallopian TubesFemaleHumansLevonorgestrelMice, Inbred C57BLMicroscopy, Electron, ScanningCalciumContraceptive Agents, HormonalContraceptives, PostcoitalLevonorgestrelProgesteroneReceptors, ProgesteroneTRPV4 protein, humanTrpv4 protein, mouseTRPV Cation Channelscalciumciliary beatlevonorgestreloviductTRPV4tubal pregnancy

Identifiers

PMID30632164
PMCPMC6593834
OpenAlexW2908905621

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.