Evidence map›Paper›PMID 30632012›Full record

SynthesisJournal of neurovirology2019

Impact of infection on risk of Parkinson's disease: a quantitative assessment of case-control and cohort studies.

Lei Meng, Liang Shen, Hong-Fang Ji

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Journal of neurovirology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
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  5. Review
  6. Article
  7. Review
  8. Consequences of COVID-19 on Adipose Tissue Signatures.International journal of molecular sciences · 2024
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
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  17. COVID-19: The cynosure of rise of Parkinson's disease.International review of neurobiology · 2022
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lei MengInstitute of Biomedical Research, Shandong University of Technology, Zibo, Shandong, People's Republic of China.
Liang ShenInstitute of Biomedical Research, Shandong University of Technology, Zibo, Shandong, People's Republic of China. shen@sdut.edu.cn.
Hong-Fang JiInstitute of Biomedical Research, Shandong University of Technology, Zibo, Shandong, People's Republic of China. jhf@sdut.edu.cn.
Shandong University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Identifying modifiable risk factors for Parkinson's disease (PD) to help prevent this disease has attracted increasing interest in recent years for the limited effective drugs at present. Despite many studies indicated that infection acts as a risk factor for PD, there is no quantitative assessment of the impact of viral and bacterial infections on the risk of developing PD. The present study performed a meta-analysis on the basis of 38 datasets from 13 studies covering 287,773 PD cases and 7,102,901 controls to ascertain the association between PD and infection and the differences in the strength of the viral and bacterial infections. The overall meta-analytic results indicated that individuals with infection had a 20% increased risk of PD compared with controls (OR 1.20, 95%CI 1.07-1.32). The subgroup analysis according to the type of infection found that bacterial infection had a significant impact on increased risk of PD (OR 1.40, 95%CI 1.32-1.48). The present analysis indicated that infection could increase the risk of developing PD, and physician should be aware of the risk of developing PD in subjects with infection.

Indexed as

Bacterial InfectionsCase-Control StudiesHelicobacter pyloriHepacivirusHepatitis B virusHerpesvirus 3, HumanHumansMeasles virusMycobacterium tuberculosisOdds RatioOrthomyxoviridaeParkinson DiseaseRiskSimplexvirusStreptococcus pyogenesVirus DiseasesBacteriaInfectionMeta-analysisParkinson’s diseaseVirus

Identifiers

PMID30632012
OpenAlexW2909509683

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.