Evidence map›Paper›PMID 30631438›Full record

ArticleF1000Research2018

Polyglutamine toxicity assays highlight the advantages of mScarlet for imaging in

Maram B Albakri, Yuwei Jiang, Julie Genereaux, Patrick Lajoie

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in F1000Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Maram B Albakri *Department of Anatomy and Cell Biology, The University of Western Ontario, London, Ontario, N6A5C1, Canada.
Yuwei Jiang *Department of Anatomy and Cell Biology, The University of Western Ontario, London, Ontario, N6A5C1, Canada.
Julie GenereauxDepartment of Anatomy and Cell Biology, The University of Western Ontario, London, Ontario, N6A5C1, Canada.
Patrick LajoieDepartment of Anatomy and Cell Biology, The University of Western Ontario, London, Ontario, N6A5C1, Canada.ORCID 0000-0002-1614-176X
Western University · CA

Funding

CIHR MOP-325538
6 · The paper itself

Abstract

Development of fluorescent proteins (FPs) enabled researchers to visualize protein localization and trafficking in living cells and organisms. The extended palette of available FPs allows simultaneous detection of multiple fluorescent fusion proteins. Importantly, FPs are originally derived from different organisms from jelly fish to corals and each FP displays its own biophysical properties. Among these properties, the tendency of FPs to oligomerize inherently affects the behavior of its fusion partner. Here we employed the budding yeast

Indexed as

Huntington DiseaseSaccharomyces cerevisiaeAnimalsPeptidesSaccharomyces cerevisiae ProteinsPeptidespolyglutamineSaccharomyces cerevisiae Proteinsaggregationfluorescent proteinsHuntington’s diseasemScarletpolyglutamine toxicityyeast

Identifiers

PMID30631438
PMCPMC6290977
OpenAlexW2886077579

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.