Evidence map›Paper›PMID 30631435›Full record

ReviewF1000Research2018

Recent advances in understanding chronic rhinosinusitis endotypes.

Eric F Succar, Justin H Turner

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. International consensus statement on allergy and rhinology: Olfaction.International forum of allergy & rhinology · 2022
    Review
  5. Review
  6. Article
  7. Article
  8. Longitudinal stability of chronic rhinosinusitis endotypes.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2019
    Article
  9. Latest advances in chronic rhinosinusitis with nasal polyps endotyping and biomarkers, and their significance for daily practice.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Eric F SuccarDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Justin H TurnerDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.ORCID 0000-0002-5501-9900
Vanderbilt University Medical Center · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
The Mechanism of Inflammation-mediated Olfactory Dysfunction in Chronic RhinosinusitisR03DC014809 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI TURNER, JUSTIN H · 2015 to 2017
$473k
NCATS NIH HHS UL1 TR000445NIAID NIH HHS L30 AI113795NIDCD NIH HHS R03 DC014809
6 · The paper itself

Abstract

Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disease with an as-yet-undefined etiology. The management of CRS has historically been phenotypically driven, and the presence or absence of nasal polyps has frequently guided diagnosis, prognosis, and treatment algorithms. Research over the last decade has begun to question the role of this distinction in disease management, and renewed attention has been placed on molecular and cellular endotyping and a more personalized approach to care. Current research exploring immunologic mechanisms, inflammatory endotypes, and molecular biomarkers has the potential to more effectively delineate distinct and clinically relevant subgroups of CRS. The focus of this review will be to discuss and summarize the endotypic characterization of CRS and the potential diagnostic and therapeutic implications of this approach to disease management.

Indexed as

RhinitisSinusitisAllergy and ImmunologyBiomarkersChronic DiseaseDisease ManagementHumansInflammationBiomarkersclustercytokineendotypenasal polypsphenotypeT-helper cell

Identifiers

PMID30631435
PMCPMC6290973
OpenAlexW2904806296

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.