Evidence map›Paper›PMID 30631343›Full record

ArticleFrontiers in genetics2018

Associations Between Genetic Data and Quantitative Assessment of Normal Facial Asymmetry.

Sara Rolfe, Su-In Lee, Linda Shapiro

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Transverse Asymmetries of the Maxilla Even in Healthy and Apparently Symmetrical Subjects.International journal of environmental research and public health · 2021
    Article
  7. Article
  8. Quantification of Facial Traits.Frontiers in genetics · 2019
    Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sara RolfeCenter for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, Seattle, WA, United States.
Su-In LeeDepartment of Genome Sciences, University of Washington, Seattle, WA, United States.
Linda ShapiroDepartment of Computer Science, University of Washington, Seattle, WA, United States.
University of Washington · USSeattle Children's Hospital · US

Funding

Technology Project: Shape-Based Retrieval of 3D Craniofacial DataU01DE020050 · NIDCR · UNIVERSITY OF WASHINGTON · PI SHAPIRO, LINDA · 2009 to 2013
$3.8M
Interaction of Genotype and Dietary Vitamin A in Cleft Lip and/or PalateF32DE025519 · NIDCR · SEATTLE CHILDREN'S HOSPITAL · PI ROLFE, SARA M · 2015 to 2018
$163k
NIDCR NIH HHS F32 DE025519NIDCR NIH HHS U01 DE020050
6 · The paper itself

Abstract

Human facial asymmetry is due to a complex interaction of genetic and environmental factors. To identify genetic influences on facial asymmetry, we developed a method for automated scoring that summarizes local morphology features and their spatial distribution. A genome-wide association study using asymmetry scores from two local symmetry features was conducted and significant genetic associations were identified for one asymmetry feature, including genes thought to play a role in craniofacial disorders and development:

Indexed as

3DMDasymmetryfacial morphologyfeature extractionGWAS

Identifiers

PMID30631343
PMCPMC6315129
OpenAlexW2903950009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.