Evidence map›Paper›PMID 30631319›Full record

ReviewFrontiers in immunology2018

Humanized Mice Are Instrumental to the Study of

Rajeev K Tyagi, Nikunj Tandel, Richa Deshpande, Robert W Engelman, Satish D Patel, Priyanka Tyagi

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Humanization of Drug Metabolism in theACS infectious diseases · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Cultivation of Asexual Intraerythrocytic Stages ofPathogens (Basel, Switzerland) · 2023
    Review
  12. Parasite Viability as a Measure ofAntimicrobial agents and chemotherapy · 2022
    Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rajeev K TyagiDivision of Gastroenterology, Hepatology and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States.
Nikunj TandelInstitute of Science, Nirma University, Ahmedabad, India.
Richa DeshpandeInstitute of Science, Nirma University, Ahmedabad, India.
Robert W EngelmanDepartment of Pediatrics, Pathology and Cell Biology, University of South Florida, Tampa, FL, United States.
Satish D PatelZydus Research Centre, Ahmedabad, India.
Priyanka TyagiDepartment of Basic and Applied Sciences, School of Engineering, GD Goenka University, Gurgaon, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research using humanized mice has advanced our knowledge and understanding of human haematopoiesis, non-adaptive and adaptive immunity, autoimmunity, infectious disease, cancer biology, and regenerative medicine. Challenges posed by the human-malaria parasite

Indexed as

AnimalsChimeraDisease Models, AnimalGenetic EngineeringHumansLife Cycle StagesMalaria, FalciparumMiceMice, SCIDPlasmodium falciparumTranslational Research, Biomedicalclodronate loaded liposomesFRG micehuHephumanized/chimeric micehuRBCsmalariaNSG miceTK/NOG mice

Identifiers

PMID30631319
PMCPMC6315153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.