Evidence map›Paper›PMID 30631252›Full record

ArticleCase reports in gastroenterology

Successful Endoscopic Closure Using Polyglycolic Acid Sheets with Fibrin Glue for Nonhealing Duodenal Ulcer with Perforation after Proton Beam Therapy of Liver Tumor.

Ko Watanabe, Takuto Hikichi, Jun Nakamura, Minami Hashimoto, Tadayuki Takagi, Rei Suzuki, Mitsuru Sugimoto, Naoki Konno, Mika Takasumi, Yuki Sato and 6 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 75% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Ko WatanabeDepartment of Endoscopy, Fukushima Medical University Hospital, Fukushima, Japan.
Takuto HikichiDepartment of Endoscopy, Fukushima Medical University Hospital, Fukushima, Japan.
Jun NakamuraDepartment of Endoscopy, Fukushima Medical University Hospital, Fukushima, Japan.
Minami HashimotoDepartment of Endoscopy, Fukushima Medical University Hospital, Fukushima, Japan.
Tadayuki TakagiDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Rei SuzukiDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Mitsuru SugimotoDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Naoki KonnoDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Mika TakasumiDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Yuki SatoDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Hiroki IrieDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Takashi KimuraDepartment of Hepato-Biliary-Pancreatic and Transplant Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan.
Akira KenjoDepartment of Hepato-Biliary-Pancreatic and Transplant Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan.
Shigeru MarubashiDepartment of Hepato-Biliary-Pancreatic and Transplant Surgery, Fukushima Medical University School of Medicine, Fukushima, Japan.
Katsutoshi ObaraDepartment of Advanced Gastrointestinal Endoscopy, Fukushima Medical University, Fukushima, Japan.
Hiromasa OhiraDepartment of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Fukushima Medical University · JPFukushima Medical University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe the first case of a nonhealing duodenal ulcer with perforation after proton beam therapy (PBT) of a liver tumor that was successfully treated endoscopically using polyglycolic acid (PGA) sheets with fibrin glue. A 69-year-old man received PBT for a liver tumor. Esophagogastroduodenoscopy (EGD) 3 months after PBT revealed a duodenal ulcer. A proton pump inhibitor was administered for 7 weeks, and the ulcer healed. Six months after the EGD, recurrence of the duodenal ulcer with perforation occurred. An emergency open surgery with placement of the omental patch was performed. However, 5 days after the surgery, because the EGD revealed a perforation site in the duodenal ulcer that was not closed, the conservative treatment was continued. Twenty-eight days after the surgery, EGD revealed that the perforation size had increased. Therefore, we conducted endoscopic closure therapy using PGA sheets with fibrin glue. Eleven days after the closure procedure, the EGD showed that the perforation site was filled with granulation tissue and was closed. Forty-nine days after the procedure, EGD revealed that the ulcer had healed. This endoscopic closure treatment was effective for a nonhealing duodenal ulcer with perforation after PBT of a liver tumor.

Indexed as

Duodenal ulcerEndoscopyPerforationPolyglycolic acidProton beam therapy

Identifiers

PMID30631252
PMCPMC6323404
OpenAlexW2902803194

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.