ArticleJournal of Indian Society of Periodontology
Comparison of gingival crevicular fluid periostin levels in healthy, chronic periodontitis, and aggressive periodontitis.
Article in Journal of Indian Society of Periodontology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Periostin level in gingival crevicular fluid in periodontal disease: a systematic review and meta-analysis.BMC oral health · 2023Pooled it
- Salivary periostin levels as a non-invasive biomarker and their clinical correlates among healthy and periodontitis patients-a cross-sectional analytical study.Frontiers in dental medicine · 2025Article
- Gingival Crevicular Fluid Biomarkers During Periodontitis Progression and After Periodontal Treatment.Journal of clinical periodontology · 2025Article
- Effect of 125 Hz and 150 Hz vibrational frequency electric toothbrushes on the rate of orthodontic tooth movement and prostaglandin E2 levels.Korean journal of orthodontics · 2023Article
- Clinical and Microbiological Profiles of Aggressive and Chronic Periodontitis in Congolese Patients: A Cross-sectional Study.Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn both states of health and disease, the integrity of connective tissue along with regulation in formation of bones are well maintained by periostin (POSTN) which is a matricellular protein secreted by fibroblasts. The present study aimed to assess the gingival crevicular fluid (GCF) POSTN levels in patients with chronic periodontitis (CP) and aggressive periodontitis and to compare them with that of healthy controls. MATERIALS AND
methodsA total of 39 individuals were recruited and allocated into the healthy group, and two periodontitis groups (the chronic and the aggressive types) (13 in each group). The samples of GCF fluid were collected using microcapillary pipette. The POSTN levels were estimated using the enzyme-linked immunosorbent assay.
resultsThe mean levels of total POSTN in GCF fluid (in pg/μl) were 182.41, 79.87, and 49.28 for the healthy, CP, aggressive periodontitis groups, respectively. There was a statistically significant difference between the groups with
conclusionThe GCF POSTN levels reduced with an increase in the severity of the periodontitis. With the present study results, we could conclude that the GCF POSTN level can be considered as a dependable marker in periodontal disease diagnosis, disease activity, and healing.
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