Evidence map›Paper›PMID 30631109›Full record

ArticleScientific reports2019

Liver Macrophage Depletion Ameliorates The Effect of Mesenchymal Stem Cell Transplantation in a Murine Model of Injured Liver.

Lobna Y Ghanem, Iman M Mansour, Nelly Abulata, Maha M Akl, Zeinab A Demerdash, Hanan G El Baz, Soheir S Mahmoud, Salwa H Mohamed, Faten S Mahmoud, Ayat S M Hassan

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Mesenchymal stem cell therapy for liver fibrosis/cirrhosis.Annals of translational medicine · 2020
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lobna Y GhanemDepartments of Electron Microscopy, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, P.O. Box 30, Giza, 12411, Egypt.
Iman M MansourDepartment of Clinical & Chemical pathology, Kasr Al-Ainy hospital, Faculty of medicine, Cairo University, Cairo, 11562, Egypt.
Nelly AbulataDepartment of Clinical & Chemical pathology, Kasr Al-Ainy hospital, Faculty of medicine, Cairo University, Cairo, 11562, Egypt.
Maha M AklDepartment of Pathology, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, P.O. Box 30, Giza, 12411, Egypt.
Zeinab A DemerdashDepartment of Immunology, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, P.O. Box 30, Giza, 12411, Egypt.
Hanan G El BazDepartment of Immunology, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, P.O. Box 30, Giza, 12411, Egypt.
Soheir S MahmoudDepartment of parasitology, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, P.O. Box 30, Giza, 12411, Egypt.
Salwa H MohamedDepartment of Immunology, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, P.O. Box 30, Giza, 12411, Egypt.
Faten S MahmoudDepartment of Immunology, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, P.O. Box 30, Giza, 12411, Egypt.
Ayat S M HassanDepartments of Electron Microscopy, Theodor Bilharz Research Institute, Warrak El-Hadar, Imbaba, P.O. Box 30, Giza, 12411, Egypt. drayatsalah@yahoo.com.
Theodor Bilharz Research Institute · EGCairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) therapy show different levels of effectiveness in the context of different types of liver damage, suggesting that the microenvironment of the injured liver is a key determinant for effective stem cell therapy. The objective was to assess the modulatory effect of hepatic stem cell niche components on the transplanted MSCs during liver injury induced by carbon tetrachloride (CCl

Indexed as

Mesenchymal Stem Cell TransplantationAnimalsBiometryCarbon TetrachlorideChemical and Drug Induced Liver InjuryDisease Models, AnimalGene Expression ProfilingHistocytochemistryImmunohistochemistryMacrophagesMiceTreatment OutcomeCarbon Tetrachloride

Identifiers

PMID30631109
PMCPMC6328636
OpenAlexW2911031127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.