ArticleScientific reports2019
Sex and age modulate antennal chemosensory-related genes linked to the onset of host seeking in the yellow-fever mosquito, Aedes aegypti.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 97 citations in OpenAlex.
- Two neuropeptides that promote blood feeding ineLife · 2026Article
- Advances and Prospects in Odour-based Management of Filth Flies.Journal of chemical ecology · 2026Review
- Differential expression of antennal chemosensory genes related to host preference of Culex pipiens biotypes.Parasites & vectors · 2025Article
- Development of a New Trapping System with Potential Implementation as a Tool for Mosquito-Borne Arbovirus Surveillance.Insects · 2025Article
- Olfactory responses of the variegated fruit fly, Phortica variegata, an emerging vector of the zoonotic eyeworm Thelazia callipaeda, to ecologically relevant volatiles.Parasites & vectors · 2025Article
- Impact of elevated COScientific reports · 2025Article
- Hematophagy Generates a Convergent Genomic Signature in Mosquitoes and Sandflies.Genome biology and evolution · 2025Article
- Aedes albopictus colonies from different geographic origins differ in their sleep and activity levels but not in the time of peak activity.Medical and veterinary entomology · 2024Article
- Rhythms in insect olfactory systems: underlying mechanisms and outstanding questions.The Journal of experimental biology · 2024Review
- Differential gene expression underpinning the production of distinct sperm morphs in the wax mothOpen biology · 2024Article
- Article
- Phenotypic variation in biting behavior associated with differences in expression of olfactory genes in the vector mosquito, Aedes albopictus (Diptera: Culicidae).Journal of medical entomology · 2024Article
- Identification and odor exposure regulation of odorant-binding proteins inFrontiers in physiology · 2024Article
- Transgenic line for characterizing GABA-receptor expression to study the neural basis of olfaction in the yellow-fever mosquito.Frontiers in physiology · 2024Article
- Context-specific variation in life history traits and behavior ofFrontiers in insect science · 2024Review
- Knockout of OR39 reveals redundancy in the olfactory pathway regulating the acquisition of host seeking inProceedings. Biological sciences · 2023Article
- Soap application alters mosquito-host interactions.iScience · 2023Article
- Towards the Laboratory Maintenance ofViruses · 2022Article
- Visual threats reduce blood-feeding and trigger escape responses in Aedes aegypti mosquitoes.Scientific reports · 2022Article
- Mosquito host-seeking diel rhythm and chemosensory gene expression is affected by age and Plasmodium stages.Scientific reports · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mosquito Aedes aegypti is the primary vector for the fastest growing infectious disease in the world, dengue fever. Disease transmission heavily relies on the ability of female mosquitoes to locate their human hosts. Additionally, males may be found in close proximity to humans, where they can find mates. Host seeking behaviour of both sexes is dependent on adult sexual maturation. Identifying the molecular basis for the onset of host seeking may help to determine targets for future vector control. In this study, we investigate modulation of the host seeking behaviour and the transcript abundance of the main chemoreceptor families between sexes and across ages in newly-emerged mosquitoes. Attraction to human odour was assessed using a Y-tube olfactometer, demonstrating that both males and females display age-dependent regulation of host seeking. The largest increase in transcript abundance was identified for select chemosensory genes in the antennae of young adult Ae. aegypti mosquitoes and reflects the increase in attraction to human odour observed between 1 and 3 day(s) post-emergence in both males and females. Future functional characterisation of the identified differentially abundant genes may provide targets for the development of novel control strategies against vector borne diseases.
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