ArticleHaematologica2019
The opposing effects of acute inflammation and iron deficiency anemia on serum hepcidin and iron absorption in young women.
Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- The Relationship Between Hepcidin-Mediated Iron Dysmetabolism and COVID-19 Severity: A Meta-Analysis.Frontiers in public health · 2022Pooled it
- Iron absorption and loss, and efficacy of iron supplementation with and without prebiotics in children with virally suppressed HIV: three prospective studies in South Africa.Nature communications · 2025Trial
- Maternal iron kinetics and maternal-fetal iron transfer in normal-weight and overweight pregnancy.The American journal of clinical nutrition · 2022Trial
- Effects of altitude and recombinant human erythropoietin on iron metabolism: a randomized controlled trial.American journal of physiology. Regulatory, integrative and comparative physiology · 2021Trial
- Altered Iron Metabolism in Dogs with Naturally Occurring Cardiac Disease.Biomolecules · 2026Article
- Surgery and Acute Stress Decrease NRF2 mRNA Expression and Promote Iron Metabolism Alteration, Oxidative Stress, and Inflammatory Gene Expression in the Liver of Prehypertensive Rats.Physiological research · 2025Article
- Combined Bioinformatic and Experimental Approaches to Analyze miR-182-3p and miR-24-3p Expression and Their Target Genes in Gestational Diabetes Mellitus and Iron Deficiency Anemia During Pregnancy.Current issues in molecular biology · 2025Article
- Impact of inflammatory status on intestinal iron absorption in older hospitalized patients.European journal of clinical nutrition · 2025Article
- HFE-Related Hemochromatosis May Be a Primary Kupffer Cell Disease.Biomedicines · 2025Review
- Combined effects of maternal supplementation of iron, calcium, folic acid, and multivitamin during pregnancy on obesity in Chinese preschoolers born macrosomia.Frontiers in pediatrics · 2025Article
- Diagnostics: Markers of Body Iron Status.Advances in experimental medicine and biology · 2025Review
- Serum hepcidin recalibrated values in Mexican schoolchildren by demographic characteristics, nutritional and infection/inflammation status.Annals of hematology · 2024Article
- Analysis of Ferritin, Hepcidin, Zinc, C-Reactive Protein and IL-6 Levels in COVID-19 in Patients Living at Different Altitudes in Peru.Biomedicines · 2024Article
- Iron deficiency and supplementation in heart failure.Nature reviews. Cardiology · 2024Review
- Predicting response to iron supplementation in patients with active inflammatory bowel disease (PRIme): a randomised trial protocol.BMJ open · 2024Article
- Article
- Hepcidin and Iron Status in Patients With Inflammatory Bowel Disease Undergoing Induction Therapy With Vedolizumab or Infliximab.Inflammatory bowel diseases · 2023Article
- Comparative analysis of oral and intravenous iron therapy in rat models of inflammatory anemia and iron deficiency.Haematologica · 2023Article
- Hepcidin regulation in Kenyan children with severe malaria and non-typhoidalHaematologica · 2022Article
- Transferrin Saturation/Hepcidin Ratio DiscriminatesInternational journal of molecular sciences · 2022Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatic hepcidin synthesis is stimulated by inflammation but inhibited during iron deficiency anemia (IDA). In humans, the relative strength of these opposing signals on serum hepcidin and the net effect on iron absorption and systemic iron recycling is uncertain. In this prospective, 45-day study, in young women (n=46; age 18-49 years) with or without IDA, we compared iron and inflammation markers, serum hepcidin and erythrocyte iron incorporation from
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.