Evidence map›Paper›PMID 30630880›Full record

ArticleG3 (Bethesda, Md.)2019

Shep RNA-Binding Capacity Is Required for Antagonism of

Dahong Chen, Margarita Brovkina, Leah H Matzat, Elissa P Lei

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Mechanisms of Interaction between Enhancers and Promoters in ThreeInternational journal of molecular sciences · 2023
    Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dahong ChenNuclear Organization and Gene Expression Section, Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, 20892.ORCID 0000-0003-4403-6788
Margarita BrovkinaNuclear Organization and Gene Expression Section, Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, 20892.
Leah H MatzatNuclear Organization and Gene Expression Section, Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, 20892.
Elissa P LeiNuclear Organization and Gene Expression Section, Laboratory of Cellular and Developmental Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, 20892 leielissa@niddk.nih.gov.ORCID 0000-0003-4894-0037
National Institutes of Health · USNational Institute of Diabetes and Digestive and Kidney Diseases · US

Funding

Chromatin Insulator Function and Nuclear OrganizationZIADK015602 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI LEI, ELISSA · 2009 to 2025
$24.7M
6 · The paper itself

Abstract

Chromatin insulators are DNA-protein complexes that regulate chromatin structure and gene expression in a wide range of organisms. These complexes also harbor enhancer blocking and barrier activities. Increasing evidence suggests that RNA molecules are integral components of insulator complexes. However, how these RNA molecules are involved in insulator function remains unclear. The

Indexed as

Gene Expression Regulation, DevelopmentalAnimalsDrosophila melanogasterDrosophila ProteinsFemaleNeuronsRecombinant ProteinsRNARNA-Binding ProteinsTranscription FactorsDrosophila Proteinsmdg4 protein (gypsy)Recombinant ProteinsRNARNA-Binding ProteinsShep protein, DrosophilaTranscription FactorsBarrier activityChromatin insulatorEnhancer blockingRNA-bindingShep

Identifiers

PMID30630880
PMCPMC6404607
OpenAlexW2909735498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.