Evidence map›Paper›PMID 30630868›Full record

ArticlePediatrics2019

Retinal Findings in Young Children With Increased Intracranial Pressure From Nontraumatic Causes.

Angell Shi, Abhaya Kulkarni, Kenneth W Feldman, Avery Weiss, Emily A McCourt, Susan Schloff, Michael Partington, Brian Forbes, Brooke E Geddie, Karin Bierbrauer and 5 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Transorbital point-of-care ultrasound versus fundoscopic papilledema to support treatment indication for potentially elevated intracranial pressure in children.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Retinal and visual function in infants with non-accidental trauma and retinal hemorrhages.Documenta ophthalmologica. Advances in ophthalmology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 11 institutions in 3 countries.

Angell ShiSidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania.
Abhaya KulkarniDivision of Neurosurgery, The Hospital for Sick Children, Toronto, Ontario, Canada.
Kenneth W FeldmanDepartments of Pediatrics and.
Avery WeissOphthalmology, Seattle Children's Hospital and School of Medicine, University of Washington, Seattle, Washington.
Emily A McCourtDepartment of Ophthalmology, Children's Hospital Colorado and School of Medicine, University of Colorado, Aurora, Colorado.
Susan SchloffAssociated Eye Care, St Paul, Minnesota.
Michael PartingtonDepartment of Neurosurgery, Gillette Children's Specialty Healthcare, St Paul, Minnesota.
Brian ForbesDivision of Ophthalmology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Brooke E GeddieDivision of Pediatric Ophthalmology, Helen DeVos Children's Hospital, Grand Rapids, Michigan.
Karin BierbrauerDivision of Pediatric Neurosurgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Paul H PhillipsHarvey and Bernice Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
David L RogersDepartment of Ophthalmology, Nationwide Children's Hospital, Columbus, Ohio.
Waleed Abed AlnabiDepartment of Pediatric Ophthalmology and Ocular Genetics, Wills Eye Hospital, Philadelphia, Pennsylvania; and.
Gil BinenbaumDivision of Ophthalmology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Alex V LevinSidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania; alevin@willseye.org.
Children's Hospital of Philadelphia · USUniversity of Washington · USWills Eye Hospital · USChildren’s Minnesota - St. Paul Hospital · USCincinnati Children's Hospital Medical Center · USGillette Children's Specialty Healthcare · USHelen DeVos Children's Hospital · USNationwide Children's Hospital · USThomas Jefferson University · USUniversity of Arkansas for Medical Sciences · USUniversity of Colorado Denver · US

Funding

PENN Vision Clinical Scientist ProgramK12EY015398 · NEI · UNIVERSITY OF PENNSYLVANIA · PI JOSHUA L DUNAIEF · 2004 to 2026
$11.7M
NEI NIH HHS K12 EY015398
6 · The paper itself

Abstract

objectivesIncreased intracranial pressure (ICP) has been suggested in legal settings as an alternative cause of retinal hemorrhages (RHs) in young children who may have sustained abusive head trauma. We assessed the prevalence and characteristics of RHs in children with increased ICP.

methodsWe conducted a prospective, multicenter study of children <4 years old with newly diagnosed increased ICP as determined by using direct measurement and/or clinical criteria. Infants who were premature, neonates, and suspected survivors of abusive head trauma were excluded on the basis of nonocular findings. Fundus examinations were performed; extent, number, and type of RH in each of 4 distinct retinal zones were recorded.

resultsFifty-six children (27 boys) were studied (mean age 15.4 months; range 1-43 months). All of the children had elevated ICP that required intervention. One child had papilledema. No child (0%; 95% confidence interval: 0%-6.4%) or eye (0%; 95% confidence interval: 0%-3.3%) was found to have an RH. Causes of increased ICP included hydrocephalus, intraventricular hemorrhage, congenital malformations, malfunctioning shunts, and the presence of intracranial space-occupying lesions.

conclusionsAlthough acute increased ICP can present in children with a pattern of peripapillary superficial RHs in the presence of papilledema, our study supports the conclusion that RHs rarely occur in the absence of optic disc swelling and do not present beyond the peripapillary area in the entities we have studied.

Indexed as

Child, PreschoolCraniocerebral TraumaFemaleHumansInfantIntracranial HypertensionIntracranial PressureMaleProspective StudiesRetinal Hemorrhage

Identifiers

PMID30630868
PMCPMC6361344
OpenAlexW2909871247

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.