ArticleAJNR. American journal of neuroradiology2019
Resting-State Functional Connectivity of the Middle Frontal Gyrus Can Predict Language Lateralization in Patients with Brain Tumors.
Article in AJNR. American journal of neuroradiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 43 citations in OpenAlex.
- Probabilistic template matching for detecting resting-state functional MRI language network in brain tumor patients.Medical physics · 2025Article
- Resting-State Functional MRI Analyses for Brain Activity Characterization: A Narrative Review of Features and Methods.The European journal of neuroscience · 2025Review
- Evolutionary Strategies Enable Systematic and Reliable Uncertainty Quantification: A Proof-of-Concept Pilot Study on Resting-State Functional MRI Language Lateralization.Journal of imaging informatics in medicine · 2025Article
- Assessing regional homogeneity and cognitive function alterations in pediatric brain tumor patients: a resting-state functional magnetic resonance imaging study.Quantitative imaging in medicine and surgery · 2024Article
- Pseudo-Resting-State Functional MRI Derived from Dynamic Susceptibility Contrast Perfusion MRI Can Predict Cognitive Impairment in Glioma.AJNR. American journal of neuroradiology · 2024Article
- Reorganization of motor network in patients with Parkinson's disease after deep brain stimulation.CNS neuroscience & therapeutics · 2024Article
- Altered brain structure in preschool-aged children with tetralogy of Fallot.Pediatric research · 2023Article
- Diffusion magnetic resonance imaging connectome features are predictive of functional lateralization of semantic processing in the anterior temporal lobes.Human brain mapping · 2023Article
- Occupation-modulated language networks and its lateralization: A resting-state fMRI study of seafarers.Frontiers in human neuroscience · 2023Article
- Altered regional homogeneity in patients with ovarian cancer treated with chemotherapy: a resting state fMRI study.Brain imaging and behavior · 2022Article
- Resting-state functional MRI language network connectivity differences in patients with brain tumors: exploration of the cerebellum and contralesional hemisphere.Brain imaging and behavior · 2022Article
- Investigation of changes in the activity and function of dry eye-associated brain regions using the amplitude of low-frequency fluctuations method.Bioscience reports · 2022Article
- General principles governing the amount of neuroanatomical overlap between languages in bilinguals.Neuroscience and biobehavioral reviews · 2021Review
- Resting-State Functional MRI for Determining Language Lateralization in Children with Drug-Resistant Epilepsy.AJNR. American journal of neuroradiology · 2021Article
- Organizing Variables Affecting fMRI Estimates of Language Dominance in Patients with Brain Tumors.Brain sciences · 2021Review
- Prior Neurosurgery Decreases fMRI Estimates of Language Laterality in Patients with Gliomas within Anterior Language Sites.Journal of clinical medicine · 2021Article
- Glioma-Induced Disruption of Resting-State Functional Connectivity and Amplitude of Low-Frequency Fluctuations in the Salience Network.AJNR. American journal of neuroradiology · 2021Article
- Developing fMRI protocol for clinical useNeurosciences (Riyadh, Saudi Arabia) · 2021Article
- Frontal White Matter Hyperintensities Effect on Default Mode Network Connectivity in Acute Mild Traumatic Brain Injury.Frontiers in aging neuroscience · 2021Article
- Chemotherapy Potentially Facilitates the Occurrence of Radiation Encephalopathy in Patients With Nasopharyngeal Carcinoma Following Radiotherapy: A Multiparametric Magnetic Resonance Imaging Study.Frontiers in oncology · 2019Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
Abstract
background and purposeA recent study using task-based fMRI demonstrated that the middle frontal gyrus is comparable with Broca's area in its ability to determine language laterality using a measure of verbal fluency. This study investigated whether the middle frontal gyrus can be used as an indicator for language-hemispheric dominance in patients with brain tumors using task-free resting-state fMRI. We hypothesized that no significant difference in language lateralization would occur between the middle frontal gyrus and Broca area and that the middle frontal gyrus can serve as a simple and reliable means of measuring language laterality. MATERIALS AND
methodsUsing resting-state fMRI, we compared the middle frontal gyrus with the Broca area in 51 patients with glial neoplasms for voxel activation, the language laterality index, and the effect of tumor grade on the laterality index. The laterality index derived by resting-state fMRI and task-based fMRI was compared in a subset of 40 patients.
resultsVoxel activations in the left middle frontal gyrus and left Broca area were positively correlated (
conclusionsThe middle frontal gyrus is comparable with the Broca area in its ability to determine hemispheric dominance for language using resting-state fMRI. Our results suggest the addition of resting-state fMRI of the middle frontal gyrus to the list of noninvasive modalities that could be used in patients with gliomas to evaluate hemispheric dominance of language before tumor resection. In patients who cannot participate in traditional task-based fMRI, resting-state fMRI offers a task-free alternate to presurgically map the eloquent cortex.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.