Evidence map›Paper›PMID 30630702›Full record

Trial reportThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2019

Two Interventions for PatientsWith Major Depression and Severe Chronic Obstructive Pulmonary Disease: Impact on Quality of Life.

Danielle S Jackson, Samprit Banerjee, Jo Anne Sirey, Cristina Pollari, Nili Solomonov, Richard Novitch, Alexandra Chalfin, Yiyuan Wu, George S Alexopoulos

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Danielle S JacksonWeill Cornell Institute of Geriatric Psychiatry (DSJ, SB, JAS, CP, NS, AC, GSA), White Plains, NY.
Samprit BanerjeeWeill Cornell Institute of Geriatric Psychiatry (DSJ, SB, JAS, CP, NS, AC, GSA), White Plains, NY; and the Weill Cornell Department of Healthcare Policy and Research (SB, YW), White Plains, NY.
Jo Anne SireyWeill Cornell Institute of Geriatric Psychiatry (DSJ, SB, JAS, CP, NS, AC, GSA), White Plains, NY.
Cristina PollariWeill Cornell Institute of Geriatric Psychiatry (DSJ, SB, JAS, CP, NS, AC, GSA), White Plains, NY.
Nili SolomonovWeill Cornell Institute of Geriatric Psychiatry (DSJ, SB, JAS, CP, NS, AC, GSA), White Plains, NY.
Richard NovitchBurke Rehabilitation Hospital (RN), White Plains, NY.
Alexandra ChalfinWeill Cornell Institute of Geriatric Psychiatry (DSJ, SB, JAS, CP, NS, AC, GSA), White Plains, NY.
Yiyuan Wuand the Weill Cornell Department of Healthcare Policy and Research (SB, YW), White Plains, NY.
George S AlexopoulosWeill Cornell Institute of Geriatric Psychiatry (DSJ, SB, JAS, CP, NS, AC, GSA), White Plains, NY. Electronic address: gsalexop@med.cornell.edu.

Funding

Relief: A Behavioral Intervention for Depression and Chronic Pain for Primary Care PracticesP50MH113838 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2017 to 2020
$5.7M
RESEARCH TRAINING IN GERIATRIC MOOD DISORDERST32MH019132 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI GUNNING, FAITH M · 1990 to 2025
$3.4M
Treating Older Patients with Major Depression and Severe COPDR01MH076829 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2008 to 2012
$1.9M
NIMH NIH HHS P50 MH113838NIMH NIH HHS R01 MH076829NIMH NIH HHS T32 MH019132
6 · The paper itself

Abstract

objectiveClinically significant depression occurs in approximately 40% of chronic obstructive pulmonary disease (COPD) patients, and both illnesses severely impair quality of life. This study tests the hypothesis that problem-solving integrated with a treatment adherence intervention, the Problem Solving-Adherence (PSA), is superior to a personalized treatment adherence intervention, the Personalized Intervention for Depressed Patients with COPD (PID-C), alone in improving quality of life in depressed COPD patients.

methodsAfter screening 633 admissions for acute rehabilitation, we studied quality of life in 87 participants with major depression (by Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition) and severe COPD randomly assigned to 14 sessions of PID-C or PSA over 26 weeks. Quality of life was assessed using the Word Health Organization Quality of Life-BREF at baseline and weeks 10, 14, and 26.

resultsThe hypothesis was not supported. Exploratory latent class growth modeling identified two quality of life trajectories. In 80.5% of participants, quality of life remained unchanged and improved in the remaining 19.5% during the first 14 weeks. Patients with a stable quality trajectory had higher qualityof life at baseline and a stronger sense of personal agency.

conclusionMaintaining quality of life is a favorable outcome in depressed patients with COPD whose course is one of deterioration. These findings highlight the usefulness of PID-C, an easy to learn, personalized adherence enhancement intervention that, after further testing, may be integrated into the rehabilitation and care of depressed COPD patients.

Indexed as

Quality of LifeAgedFemaleHumansMajor Depressive DisorderMalePrecision MedicineProblem SolvingPulmonary Disease, Chronic ObstructiveTreatment Adherence and Complianceclinical trialCOPDDepressionpersonalized interventionquality of life

Identifiers

PMID30630702
PMCPMC6443466

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.