ArticleBMC genomics2019
Probe-based association analysis identifies several deletions associated with average daily gain in beef cattle.
Article in BMC genomics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 32 citations in OpenAlex.
- Genome-Wide Association Study Identifies Candidate Genes for Body Size Traits in Wanyue Black Pigs.Animals : an open access journal from MDPI · 2025Article
- Integrative analysis identifies LHFPL6 as a CAF-specific prognostic biomarker in colorectal cancer.Clinical and experimental medicine · 2025Article
- Transcriptome remodelling and changes in growth and cardiometabolic phenotype result following Grb10a knockdown in the early life of the zebrafish.Cellular and molecular life sciences : CMLS · 2025Article
- The impact of myostatin variants on growth traits in South African Bonsmara beef cattle.Tropical animal health and production · 2024Article
- Genome-wide association studies for economically important traits in mink using copy number variation.Scientific reports · 2024Article
- Genetic Association Analysis of Copy Number Variations for Meat Quality in Beef Cattle.Foods (Basel, Switzerland) · 2023Article
- Article
- Favored single nucleotide variants identified using whole genome Re-sequencing of Austrian and Chinese cattle breeds.Frontiers in genetics · 2022Article
- Runs of homocigosity and its association with productive traits in Mexican Holstein cattle.PloS one · 2022Article
- Genome-wide detection of CNV regions and their potential association with growth and fatness traits in Duroc pigs.BMC genomics · 2021Article
- The transcriptome-wide association search for genes and genetic variants which associate with BMI and gestational weight gain in women with type 1 diabetes.Molecular medicine (Cambridge, Mass.) · 2021Article
- Genome-Wide Detection of Copy Number Variations and Their Association With Distinct Phenotypes in the World's Sheep.Frontiers in genetics · 2021Article
- Effect of Aging Time on Meat Quality of Longissimus Dorsi from Yunling Cattle: A New Hybrid Beef Cattle.Animals : an open access journal from MDPI · 2020Article
- Selection signatures in two oldest Russian native cattle breeds revealed using high-density single nucleotide polymorphism analysis.PloS one · 2020Article
- Genomic Prediction and Association Analysis with Models Including Dominance Effects for Important Traits in Chinese Simmental Beef Cattle.Animals : an open access journal from MDPI · 2019Article
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAverage daily gain (ADG) is an important trait that contributes to the production efficiency and economic benefits in the beef cattle industry. The molecular mechanisms of ADG have not yet been fully explored because most recent association studies for ADG are based on SNPs or haplotypes. We reported a systematic CNV discovery and association analysis for ADG in Chinese Simmental beef cattle.
resultsOur study identified 4912 nonredundant CNVRs with a total length of ~ 248.7 Mb, corresponding to ~ 8.9% of the cattle genome. Using probe-based CNV association, we identified 24 and 12 significant SNP probes within five deletions and two duplications for ADG, respectively. Among them, we found one common deletion with 89 kb imbedded in LHFPL Tetraspan Subfamily Member 6 (LHFPL6) at 22.9 Mb on BTA12, which has high frequency (12.9%) dispersing across population. CNV selection test using V
conclusionsOur results provided some valuable insights to elucidate the genetic basis of ADG in beef cattle, and these findings offer an alternative perspective to understand the genetic mechanism of complex traits in terms of copy number variations in farm animals.
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