Evidence map›Paper›PMID 30629845›Full record

Trial reportPediatric obesity2019

Early rapid weight gain among formula-fed infants: Impact of formula type and maternal feeding styles.

J A Mennella, M A Papas, A R Reiter, V A Stallings, J C Trabulsi

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Pediatric obesity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01700205 (Impact of Diet Composition on Energy Balance and Satiety During Infancy), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01700205 nacompletednot on this map

Impact of Diet Composition on Energy Balance and Satiety During Infancy

TypeinterventionalSponsorMonell Chemical Senses CenterRan2012 to 2016Enrolled113ConditionsDevelopmentArmsType of Formula
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 50 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. The care of infants with rapid weight gain: Should we be doing more?Journal of paediatrics and child health · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

J A MennellaMonell Chemical Senses Center, Philadelphia, Pennsylvania.ORCID 0000-0002-8855-0204
M A PapasChristiana Care Health System Value Institute, Newark, Delaware.
A R ReiterMonell Chemical Senses Center, Philadelphia, Pennsylvania.
V A StallingsDivision of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
J C TrabulsiDepartment of Behavioral Health and Nutrition, University of Delaware College of Health and Sciences, Newark, Delaware.
Monell Chemical Senses Center · USChildren's Hospital of Philadelphia · USChristiana Care Health System · USDepartment of Behavioral Health · US

Funding

Impact of diet composition during infancy on energy balance, satiety and growthR01HD072307 · NICHD · MONELL CHEMICAL SENSES CENTER · PI MENNELLA, JULIA ANNE, TRABULSI, JILLIAN CHRISTINE · 2012 to 2016
$2.7M
Secondary Analyses of RCT Data on Infant Formula and Nutritional ProgrammingR03HD094908 · NICHD · MONELL CHEMICAL SENSES CENTER · PI MENNELLA, JULIA ANNE, TRABULSI, JILLIAN CHRISTINE · 2018 to 2019
$173k
NICHD NIH HHS R01 HD072307NICHD NIH HHS R01HD072307NICHD NIH HHS R03HD09408NICHD NIH HHS R03 HD094908
6 · The paper itself

Abstract

backgroundWhat and how infants are fed are considered important determinants for the risk factor of early rapid gain weight.

objectivesWe conducted secondary analyses on data from a randomized clinical trial, wherein infants randomized to feed cow milk formula had double the incidence of early rapid weight gain than those fed extensively hydrolyzed protein formula, to determine whether maternal feeding styles had independent effects or interactive effects with infant formula type on early rapid weight gain.

methodsAnthropometry and feeding patterning (number of daily formula feeds) were measured monthly, and maternal feeding styles were measured at 0.5, 3.5, and 4.5 months. Longitudinal models were fitted using generalized estimating equations and separate logistic models conducted.

resultsThe treatment groups did not differ in formula feeding patterning or in maternal feeding styles, which were stable across the first 4.5 months. Feeding styles had no significant effects on early rapid weight gain and did not interact with formula group. However, type of infant formula had a direct and independent impact on early rapid weight gain (P = 0.003).

conclusionsThe type of infant formula had a differential impact on early rapid weight gain independent of maternal feeding style, highlighting the self-regulatory capabilities of infants.

Indexed as

Feeding BehaviorInfant FormulaAdultAnimalsAnthropometryCattleFemaleHumansInfant, NewbornMaleWeight Gaininfant formulamaternal feeding stylespatterning of feedingrapid weight gain

Identifiers

PMID30629845
PMCPMC6594394
OpenAlexW2910245110

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.