ArticleStem cells (Dayton, Ohio)2019
Hypoxia Prevents Mitochondrial Dysfunction and Senescence in Human c-Kit
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Article in Stem cells (Dayton, Ohio), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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32citing papers in PubMed
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Who cites it
32 citing papers in PubMed.
- Cardiac Mitochondrial Dysfunction Following Bleomycin-Induced Acute Lung Injury in Rats.bioRxiv : the preprint server for biology · 2026Article
- A novel culture flask for clinostat-based simulation of extraterrestrial gravities.Frontiers in cell and developmental biology · 2026Article
- Mitochondrial Damage and Autophagy Dysregulation in Alzheimer's Disease: Mechanisms and Therapeutic Opportunities.Neurochemical research · 2025Review
- Short-Term DMOG treatment rejuvenates senescent mesenchymal stem cells by enhancing mitochondrial function and mitophagy through the HIF-1α/BNIP3 pathway.Stem cell research & therapy · 2025Article
- The Role of NADAmerican journal of cardiovascular drugs : drugs, devices, and other interventions · 2025Review
- Targeting Mitochondrial Dysfunction in Cerebral Ischemia: Advances in Pharmacological Interventions.Antioxidants (Basel, Switzerland) · 2025Review
- Autophagy as a Guardian of Vascular Niche Homeostasis.International journal of molecular sciences · 2024Review
- Single-cell transcriptome reveals a novel mechanism of C-KitCell & bioscience · 2024Article
- Targeting the redox system for cardiovascular regeneration in aging.Aging cell · 2023Review
- Unravelling the Interplay between Cardiac Metabolism and Heart Regeneration.International journal of molecular sciences · 2023Review
- Surface Lin28A expression consistent with cellular stress parallels indicators of senescence.Cardiovascular research · 2023Article
- A multi-omics longitudinal aging dataset in primary human fibroblasts with mitochondrial perturbations.Scientific data · 2022Article
- Autophagy Enhances Longevity of Induced Pluripotent Stem Cell-Derived Endothelium via mTOR-Independent ULK1 Kinase.Stem cells translational medicine · 2022Article
- The Mito-Hormetic Mechanisms of Ozone in the Clearance of SARS-CoV2 and in the COVID-19 Therapy.Biomedicines · 2022Review
- The Vascular Niche for Adult Cardiac Progenitor Cells.Antioxidants (Basel, Switzerland) · 2022Review
- Targeting NAD+: is it a common strategy to delay heart aging?Cell death discovery · 2022Review
- Epigenetic Alterations under Oxidative Stress in Stem Cells.Oxidative medicine and cellular longevity · 2022Review
- Article
- Rejuvenating the Aging Heart by Enhancing the Expression of theInternational journal of molecular sciences · 2021Article
- Article
Corrections and comments
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Authors and funding
12 authors.
Kelli I KorskiDepartment of Biology and Integrated Regenerative Research Institute, San Diego State University, San Diego, California, USA.
Dieter A KubliDepartment of Biology and Integrated Regenerative Research Institute, San Diego State University, San Diego, California, USA.ORCID 0000-0001-7970-4075
Bingyan J WangDepartment of Biology and Integrated Regenerative Research Institute, San Diego State University, San Diego, California, USA.
Farid G KhalafallaDepartment of Biology and Integrated Regenerative Research Institute, San Diego State University, San Diego, California, USA.ORCID 0000-0003-3907-9716
Megan M MonsantoDepartment of Biology and Integrated Regenerative Research Institute, San Diego State University, San Diego, California, USA.
Fareheh FirouziDepartment of Biology and Integrated Regenerative Research Institute, San Diego State University, San Diego, California, USA.
Oscar H EcheagarayDepartment of Biology and Integrated Regenerative Research Institute, San Diego State University, San Diego, California, USA.
Taeyong KimDepartment of Biology and Integrated Regenerative Research Institute, San Diego State University, San Diego, California, USA.
Robert M AdamsonDivision of Cardiology, Sharp Hospital, San Diego, California, USA.
Walter P DembitskyDivision of Cardiology, Sharp Hospital, San Diego, California, USA.
Åsa B GustafssonThe Skaggs School of Pharmacy and Pharmaceutical Sciences, Department of Pharmacology, University of California San Diego, La Jolla, California, USA.
Mark A SussmanDepartment of Biology and Integrated Regenerative Research Institute, San Diego State University, San Diego, California, USA.ORCID 0000-0002-0104-4799
Funding
Surgery, Physiology and ImmunohistopathologyP01HL085577 · NHLBI · SAN DIEGO STATE UNIVERSITY · PI SUSSMAN, MARK ALAN · 2006 to 2017
$18.4MRegulation of Signal Transduction to Treat Heart FailureR01HL067245 · NHLBI · SAN DIEGO STATE UNIVERSITY · PI SUSSMAN, MARK ALAN · 2001 to 2021
$6.0MStem Cell Signaling in the Pathologically Challenged MyocardiumR37HL091102 · NHLBI · SAN DIEGO STATE UNIVERSITY · PI SUSSMAN, MARK ALAN · 2008 to 2017
$3.8MBeta-adrenergic signaling: double edged sword of myocardial repairR01HL117163 · NHLBI · SAN DIEGO STATE UNIVERSITY · PI SUSSMAN, MARK ALAN · 2013 to 2017
$1.9MAntagonism of myocardial aging and senescence with Pim-1 kinaseR01HL105759 · NHLBI · SAN DIEGO STATE UNIVERSITY · PI SUSSMAN, MARK ALAN · 2011 to 2015
$1.8MResolving myocardial regeneration by tracking commitment of c-Kit+ cellsR01HL135661 · NHLBI · SAN DIEGO STATE UNIVERSITY · PI GUDE, NATALIE ALLEN, SUSSMAN, MARK ALAN · 2017 to 2020
$1.7MEnhanced Myocardial Repair with CardioClusters and CardioChimerasR01HL122525 · NHLBI · SAN DIEGO STATE UNIVERSITY · PI SUSSMAN, MARK ALAN · 2014 to 2017
$1.5MNext Generation Regenerative Therapy with Pim-1 Enhanced Cardiac Progenitor CellsR41HL137602 · NHLBI · CARDIOCREATE, INC. · PI SUSSMAN, MARK ALAN · 2017 to 2017
$266kStemness and Differentiation Potential Are Defined by Metabolism in Cardiac Progenitor CellsF32HL136064 · NHLBI · SAN DIEGO STATE UNIVERSITY · PI KUBLI, DIETER ANDRE · 2017 to 2018
$122kNHLBI NIH HHS F32 HL136064NHLBI NIH HHS P01 HL085577NHLBI NIH HHS R01 HL067245NHLBI NIH HHS R01 HL105759NHLBI NIH HHS R01 HL117163NHLBI NIH HHS R01 HL122525NHLBI NIH HHS R01 HL135661NHLBI NIH HHS R37 HL091102NHLBI NIH HHS R41 HL137602
Abstract
Senescence-associated dysfunction deleteriously affects biological activities of human c-Kit
Indexed as
Cell HypoxiaCell ProliferationCells, CulturedCellular SenescenceHumansMitochondriaMyocytes, CardiacProto-Oncogene Proteins c-kitStem CellsProto-Oncogene Proteins c-kitAutophagyHeartHumanMitochondriaReactive oxygen speciesStem cells
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.