ArticlePloS one2019
Validation of the extended thrombolysis in cerebral infarction score in a real world cohort.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Rethinking reperfusion metrics in endovascular stroke therapy: the limitations of mTICI and a path forward toward more meaningful outcomes.Neuroradiology · 2026Article
- The thrombectomy in limb ischemia score (TILI-Score): score proposal and results of an interobserver readability survey.The international journal of cardiovascular imaging · 2026Article
- Real-World Recanalization Outcomes of Mechanical Thrombectomy in India: A Systematic Review and Meta-Analysis of Observational Studies.Asian journal of neurosurgery · 2025Review
- Incomplete reperfusion and the presence of distal emboli in predicting clinical outcome after endovascular thrombectomy.BMJ surgery, interventions, & health technologies · 2025Article
- Safety assessment of symptomatic intracranial atherosclerotic stenosis: a comparison between sole balloon angioplasty and medical treatment.Frontiers in neurology · 2025Article
- A Deep Learning Approach to Predict Recanalization First-Pass Effect following Mechanical Thrombectomy in Patients with Acute Ischemic Stroke.AJNR. American journal of neuroradiology · 2024Article
- Left Ventricular Diastolic Dysfunction Is Associated with Poor Functional Outcomes after Endovascular Thrombectomy.Journal of cardiovascular development and disease · 2024Article
- Collateral Status Modification of the Association Between Blood Pressure Variation Within 72 Hours After Endovascular Treatment and Clinical Outcome in Acute Ischemic Stroke: A Retrospective Cohort Study.Clinical interventions in aging · 2023Article
- Heterogeneity of the Relative Benefits of TICI 2c/3 over TICI 2b50/2b67 : Are there Patients who are less Likely to Benefit?Clinical neuroradiology · 2022Article
- Embotrap Extraction & Clot Evaluation & Lesion Evaluation for NeuroThrombectomy (EXCELLENT) Registry design and methods.Journal of neurointerventional surgery · 2022Article
- Is a picture-perfect thrombectomy necessary in acute ischemic stroke?Journal of neurointerventional surgery · 2022Article
- An Optimal Animal Model of Ischemic Stroke Established by Digital Subtraction Angiography-Guided Autologous Thrombi in Cynomolgus Monkeys.Frontiers in neurology · 2022Article
- Interobserver Agreement in Scoring Angiographic Results of Basilar Artery Occlusion Stroke Therapy.AJNR. American journal of neuroradiology · 2021Article
- Modelling the impact of clot fragmentation on the microcirculation after thrombectomy.PLoS computational biology · 2021Article
- First Pass Recanalization Rates of Solitaire vs Trevo vs Primary Aspiration: The Kaiser Southern California Experience.The Permanente journal · 2020Article
- Evolution of Stroke Thrombectomy Techniques to Optimize First-Pass Complete Reperfusion.Seminars in interventional radiology · 2020Review
- Sub-angiographic peripheral emboli in high resolution DWI after endovascular recanalization.Journal of neurology · 2020Article
- Optimizing Stroke Care for Patients with Large Vessel Occlusions: Current State of the Art and Future Directions.Journal of neuroendovascular therapy · 2020Review
- Effect of Balloon Guide Catheter Utilization on the Incidence of Sub-angiographic Peripheral Emboli on High-Resolution DWI After Thrombectomy: A Prospective Observational Study.Frontiers in neurology · 2020Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA thrombolysis in cerebral infarction (TICI) score of 2b is defined as a good recanalization result although the reperfusion may only cover 50% of the affected territory. An additional mTICI2c category was introduced to further differentiate between mTICI scores. Despite the new mTICI2c category, mTICI2b still covers a range of 50-90% reperfusion which might be too imprecise to predict neurological improvement after therapy.
aimTo compare the 7-point "expanded TICI" (eTICI) scale with the traditional mTICI in regard to predict functional independence at 90 days.
methodsRetrospective review of 225 patients with large artery occlusion. Angiograms were graded by 2 readers according the 7-point eTICI score (0% = eTICI0; reduced clot = eTICI1; 1-49% = eTICI2a, 50-66% = eTICI2b50; 67-89% = eTICI2b67, 90-99% = eTICI2c and complete reperfusion = eTICI3) and the conventional mTICI score. The ability of e- and mTICI to predict favorable outcome at 90days was compared.
resultsGiven the ROC analysis eTICI was the better predictor of favorable outcome (p-value 0.047). Additionally, eTICI scores 2b50, 2b67 and 2c (former mTICI2b) were significantly superior at predicting the probability of a favorable outcome at 90 days after endovascular therapy with a p-value of 0.033 (probabilities of 17% for mTICI2b50, 24% for mTICI2b67 and 54% for mTICI2c vs. 36% for mTICI2b).
conclusionsThe 7-point eTICI allows for a more accurate outcome prediction compared to the mTICI score because it refines the broad range of former mTICI2b results.
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