Evidence map›Paper›PMID 30629593›Full record

ArticlePLoS neglected tropical diseases2019

Economic burden of dengue in Indonesia.

Mardiati Nadjib, Ery Setiawan, Septiara Putri, Joshua Nealon, Sophie Beucher, Sri Rezeki Hadinegoro, Vetty Yulianty Permanasari, Kurnia Sari, Tri Yunis Miko Wahyono, Erna Kristin and 2 more

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Enhancing Entomological Surveillance to CombatJournal of tropical medicine · 2026
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  8. Observational
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  16. Untapped Potential: A Qualitative Study of a Hospital-Based Dengue Surveillance System.The American journal of tropical medicine and hygiene · 2020
    Article
  17. Cost-Effectiveness of Dengue Vaccination in Indonesia: Considering Integrated Programs withInternational journal of environmental research and public health · 2020
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mardiati NadjibHealth Policy and Administration Department, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia.ORCID 0000-0001-8676-7525
Ery SetiawanCentre for Health Economics and Policy Studies, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia.
Septiara PutriCentre for Health Economics and Policy Studies, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia.
Joshua NealonSanofi Pasteur, Asia & JPAC region, Singapore.
Sophie BeucherSanofi Pasteur, Asia & JPAC region, Singapore.
Sri Rezeki HadinegoroFaculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta, Indonesia.
Vetty Yulianty PermanasariCentre for Health Economics and Policy Studies, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia.
Kurnia SariCentre for Health Economics and Policy Studies, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia.
Tri Yunis Miko WahyonoDepartment of Epidemiology, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia.
Erna KristinDepartment of Pharmacology & Therapy, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Dewa Nyoman WirawanFaculty of Medicine, Universitas Udayana, Denpasar, Bali.
Hasbullah ThabranyCentre for Health Economics and Policy Studies, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDengue is associated with significant economic expenditure and it is estimated that the Asia Pacific region accounts for >50% of the global cost. Indonesia has one of the world's highest dengue burdens; Aedes aegypti and Aedes albopictus are the primary and secondary vectors. In the absence of local data on disease cost, this study estimated the annual economic burden during 2015 of both hospitalized and ambulatory dengue cases in Indonesia.

methodsTotal 2015 dengue costs were calculated using both prospective and retrospective methods using data from public and private hospitals and health centres in three provinces: Yogyakarta, Bali and Jakarta. Direct costs were extracted from billing systems and claims; a patient survey captured indirect and out-of-pocket costs at discharge and 2 weeks later. Adjustments across sites based on similar clinical practices and healthcare landscapes were performed to fill gaps in cost estimates. The national burden of dengue was extrapolated from provincial data using data from the three sites and applying an empirically-derived epidemiological expansion factor.

resultsTotal direct and indirect costs per dengue case assessed at Yogyakarta, Bali and Jakarta were US$791, US$1,241 and US$1,250, respectively. Total 2015 economic burden of dengue in Indonesia was estimated at US$381.15 million which comprised US$355.2 million for hospitalized and US$26.2 million for ambulatory care cases.

conclusionDengue imposes a substantial economic burden for Indonesian public payers and society. Complemented with an appropriate weighting method and by accounting for local specificities and practices, these data may support national level public health decision making for prevention/control of dengue in public health priority lists.

Indexed as

Health Care CostsHealth ExpendituresAdolescentAdultAgedAged, 80 and overAnimalsChildChild, PreschoolDengueFemaleHumansIndonesiaInfantInfant, NewbornMale

Identifiers

PMID30629593
PMCPMC6343936

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.