Evidence map›Paper›PMID 30629488›Full record

ArticleIEEE transactions on bio-medical engineering2019

3-D Microwave Tomography Using the Soft Prior Regularization Technique: Evaluation in Anatomically Realistic MRI-Derived Numerical Breast Phantoms.

Amir H Golnabi, Paul M Meaney, Shireen D Geimer, Keith D Paulsen

Abstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amir H Golnabi
Paul M Meaney
Shireen D Geimer
Keith D Paulsen

Funding

Microwave Imaging for Neoadjuvant Chemotherapy MonitoringR01CA191227 · NCI · DARTMOUTH COLLEGE · PI MEANEY, PAUL M · 2015 to 2019
$3.6M
NCI NIH HHS R01 CA191227
6 · The paper itself

Abstract

objectiveFusion of magnetic resonance imaging (MRI) breast images with microwave tomography is accomplished through a soft prior technique, which incorporates spatial information (from MRI), i.e., accurate boundary location of different regions of interest, into the regularization process of the microwave image reconstruction algorithm.

methodsNumerical experiments were completed on a set of three-dimensional (3-D) breast geometries derived from MR breast data with different parenchymal densities, as well as a simulated tumor to evaluate the performance over a range of breast shapes, sizes, and property distributions.

resultsWhen the soft prior regularization technique was applied, both permittivity and conductivity relative root mean square error values decreased by more than 87% across all breast densities, except in two cases where the error decrease was only 55% and 78%. In addition, the incorporation of structural priors increased contrast between tumor and fibroglandular tissue by 59% in permittivity and 192% in conductivity.

conclusionThis study confirmed that the soft prior algorithm is robust in 3-D and can function successfully across a range of complex geometries and tissue property distributions. SIGNIFICANCE: This study demonstrates that our microwave tomography is capable of recovering accurate tissue property distributions when spatial information from MRI is incorporated through soft prior regularization.

Indexed as

Microwave ImagingPhantoms, ImagingBreastBreast NeoplasmsFemaleHumansImaging, Three-DimensionalModels, BiologicalMultimodal ImagingTomography

Identifiers

PMID30629488
PMCPMC6620171

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.