Evidence map›Paper›PMID 30629306›Full record

Trial reportHead & neck2019

The impact of time after radiation treatment on dysphagia in patients with head and neck cancer enrolled in a swallowing therapy program.

Douglas J Van Daele, Susan E Langmore, Gintas P Krisciunas, Cathy L Lazarus, Barbara R Pauloski, Timothy M McCulloch, Gary D Gramigna, Barbara P Messing, Cynthia W Wagner, Sarah L Mott

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Head & neck, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Dysphagia Advances in Head and Neck Cancer.Current otorhinolaryngology reports · 2023
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Douglas J Van DaeleProfessor - Otolaryngology, University of Iowa.
Susan E LangmoreProfessor - Otolaryngology, Boston University Medical Center.
Gintas P KrisciunasResearch Scientist - Otolaryngology, Boston University Medical Center.
Cathy L LazarusAssociate Professor - Otolaryngology, Mount Sinai Health System.
Barbara R PauloskiAssociate Professor - Communication Sciences and Disorders, University of Wisconsin Milwaukee.
Timothy M McCullochProfessor - Otolaryngology, University of Wisconsin Madison.
Gary D GramignaLead Speech Pathologist, VA Boston Healthcare System.
Barbara P MessingSpeech Language Pathologist, Johns Hopkins Voice Center.
Cynthia W WagnerClinical Services Manager, Beth Israel Deaconess Medical Center.
Sarah L MottStatistician - Holden Comprehensive Cancer Center, University of Iowa.

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Christopher K Laubenthal · 2000 to 2026
$70.0M
Efficacy of Electrical Stimulation for Dysphagia in Head & Neck Cancer PatientsR01CA120950 · NCI · BOSTON MEDICAL CENTER · PI LANGMORE, SUSAN E · 2007 to 2011
$2.6M
NCI NIH HHS R01 CA120950
6 · The paper itself

Abstract

backgroundSwallowing dysfunction after radiotherapy (RT) for head and neck cancer can be devastating. A randomized control trial compared swallow exercises versus exercise plus neuromuscular electrical stimulation therapy and found no overall difference in outcomes.

methodsQuality of life (QOL), diet, and swallowing variables collected at discrete intervals on 117 patients were reanalyzed to test the hypothesis that shorter time between the completion of radiotherapy and beginning of the swallowing therapy program yielded improved outcomes.

resultsAt baseline, subjects < 1 year post radiation had significantly better function than subjects >2 years post RT in several measures. Over the therapy program, the early group showed significant improvement in diet and QOL. Swallowing physiologic variables showed no difference between groups.

conclusionBeginning a swallowing therapy program within 1 year of completion of radiotherapy demonstrates more consistent improvement in QOL and diet performance compared to later periods.

Indexed as

Electric Stimulation TherapyExercise TherapyDeglutitionDeglutition DisordersFemaleHead and Neck NeoplasmsHumansMaleQuality of LifeTime FactorsTreatment Outcomedysphagiahead and neck cancerneuromuscular electrical stimulationrehabilitationswallowing

Identifiers

PMID30629306
PMCPMC6382558

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.