Evidence map›Paper›PMID 30628888›Full record

ArticleeLife2019

Nagarajan Nandagopal, Leah A Santat, Michael B Elowitz

Open access · goldAbstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 106 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Developmental regulation of intestinalbioRxiv : the preprint server for biology · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. EphA2 and Ephrin-A1 Utilize the Same Interface for BothbioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. NOTCH3 and Pulmonary Arterial Hypertension.International journal of molecular sciences · 2024
    Review
  17. Review
  18. Article
  19. Progress to Clarify HowBiomolecules · 2024
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nagarajan Nandagopal *Division of Biology and Biological Engineering, California Institute of Technology, Howard Hughes Medical Institute, Pasadena, United States.ORCID 0000-0002-0469-6549
Leah A Santat *Division of Biology and Biological Engineering, California Institute of Technology, Howard Hughes Medical Institute, Pasadena, United States.ORCID 0000-0003-0511-9740
Michael B ElowitzDivision of Biology and Biological Engineering, California Institute of Technology, Howard Hughes Medical Institute, Pasadena, United States.ORCID 0000-0002-1221-0967
California Institute of Technology · US

Funding

Quantitative Single-Cell Analysis of Mammalian Notch Signaling StatesR01HD075335 · NICHD · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ELOWITZ, MICHAEL B · 2012 to 2024
$3.7M
Defense Sciences Office, DARPA HR0011-16-0138Howard Hughes Medical Institute Graduate Student FellowshipHoward Hughes Medical Institute M.B.E.Howard Hughes Medical Institute MBENational Science Foundation EFRI 1137269NICHD NIH HHS R01 HD075335NIH HHS R01 HD075335
6 · The paper itself

Abstract

The Notch signaling pathway consists of transmembrane ligands and receptors that can interact both within the same cell (

Indexed as

LigandsSignal TransductionAnimalsCaco-2 CellsCalcium-Binding ProteinsCHO CellsCricetulusHumansMembrane ProteinsMiceModels, TheoreticalNeural Stem CellsProtein BiosynthesisReceptors, NotchCalcium-Binding ProteinsDLK1 protein, humanLigandsMembrane ProteinsReceptors, Notchcis-activationcis-inhibitioncomputational biologydevelopmental biologyNotch signaling pathwaysingle cell analysissystems biology

Identifiers

PMID30628888
PMCPMC6345567
OpenAlexW2798985900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.