Evidence map›Paper›PMID 30628799›Full record

ArticlePersonality disorders2019

Disinhibited attachment behavior among infants of mothers with borderline personality disorder, depression, and no diagnosis.

Karlen Lyons-Ruth, Caitlin Riley, Matthew P H Patrick, R Peter Hobson

Open access · hybridAbstract read
In one paragraph

Article in Personality disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Maternal caregiving moderates relations between maternal childhood maltreatment and infant cortisol regulation.Journal of child psychology and psychiatry, and allied disciplines · 2025
    Article
  3. Article
  4. Is neglect the first form of threat?Attachment & human development · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Maternal interpersonal problems and attachment security in adolescent offspring.Borderline personality disorder and emotion dysregulation · 2022
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Karlen Lyons-RuthDepartment of Psychiatry.
Caitlin RileyDepartment of Psychology.
Matthew P H PatrickDepartment of Psychiatry, South London and Maudsley NHS Foundation Trust.
R Peter HobsonDepartment of Psychiatry, Tavistock Clinic and Institute of Child Health, University College London.
South London and Maudsley NHS Foundation Trust · GBThe Tavistock and Portman NHS Foundation Trust · GB

Funding

Neurobiology of Mothering and Infant StressR01HD079484 · NICHD · MCLEAN HOSPITAL · PI BOSQUET ENLOW, MICHELLE A, GRANT, PATRICIA ELLEN · 2015 to 2019
$3.6M
Psychopathology and Controlling Behavior in Adolescents.R01MH062030 · NIMH · CAMBRIDGE HEALTH ALLIANCE · PI LYONS-RUTH, KARLEN · 2001 to 2004
$946k
Baily Thomas Charitable FundHarvard CollegeHayward FoundationNICHD NIH HHS R01 HD079484NIMH NIH HHS R01 MH062030United Kingdom National Health R&D BudgetWinnicott Trust
6 · The paper itself

Abstract

Disinhibited attachment behavior is related to early institutional rearing and to later social maladaptation. It is also seen among infants reared at home whose mothers have histories of child maltreatment or psychiatric hospitalization. However, little is known about the maternal psychiatric diagnoses that might be associated with disinhibited behavior or the mechanisms through which maternal diagnosis might influence infant behavior. In the current study (N = 59), 2 maternal diagnoses, borderline personality disorder (BPD; n = 13) and depression (n = 15), were compared with a no diagnosis group (n = 31) on extent of infant disinhibited behavior. Disinhibited infant behavior was assessed at infant age of 12-18 months using the validated Rating of Infant-Stranger Engagement. Mother-infant interaction was coded using the Atypical Maternal Behavior Instrument for Assessment and Classification. Results indicated that infants of mothers with BPD were significantly more likely to be rated as disinhibited in their behavior toward the stranger compared with infants of mothers with depression and with no diagnosis. Disinhibited behavior was further related to the quality of mother-infant interaction, and maternal frightened/disoriented interaction partially mediated the effect of maternal BPD on infant disinhibited behavior. Disinhibited behavior among previously institutionally reared infants is relatively resistant to intervention after toddlerhood and is associated with maladaptation into adolescence. Therefore, high priority should be placed on understanding the developmental trajectories of home-reared infants with disinhibited behavior and on providing early assessment and early parenting support to mothers with BPD. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Indexed as

Mother-Child RelationsAdultBorderline Personality DisorderDepressive DisorderFemaleHumansInfantInfant BehaviorMaleMaternal BehaviorReactive Attachment DisorderYoung Adult

Identifiers

PMID30628799
PMCPMC6404520
OpenAlexW2909845300

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.