Evidence map›Paper›PMID 30628574›Full record

ArticleThe American journal of tropical medicine and hygiene2019

Case Report: Birth Outcome and Neurodevelopment in Placental Malaria Discordant Twins.

Andrea L Conroy, Paul Bangirana, Mary K Muhindo, Abel Kakuru, Prasanna Jagannathan, Robert O Opoka, Edward A Liechty, Miriam Nakalembe, Moses R Kamya, Grant Dorsey and 1 more

Registry-linked trialOpen access · bronzeAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02163447 (Reducing the Burden of Malaria in HIV-uninfected Pregnant Women and Infants), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02163447 phase3completednot on this map

Reducing the Burden of Malaria in HIV-uninfected Pregnant Women and Infants (PROMOTE Birth Cohort 1)

TypeinterventionalSponsorGrant Dorsey, M.D, Ph.D.Ran2014 to 2018Enrolled300ConditionsMalariaArmsMonthly dihydroartemisinin-piperaquine (DP) for adult women during pregnancy, 3 dose dihydroartemisinin-piperaquine (DP) for adult women during pregnancy, 3 dose sulfadoxine-pyrimethamine (SP) for adult women during pregnancy, Monthly dihydroartemisinin-piperaquine (DP) for infants, 3-monthly dihydroartemisinin-piperaquine (DP) for infants
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Observational
  6. Establishing a conceptual framework of the impact of placental malaria on infant neurodevelopment.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Andrea L ConroyDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana.
Paul BangiranaDepartment of Psychiatry, Makerere University College of Health Sciences, Kampala, Uganda.
Mary K MuhindoInfectious Diseases Research Collaboration, Kampala, Uganda.
Abel KakuruInfectious Diseases Research Collaboration, Kampala, Uganda.
Prasanna JagannathanDivision of Infectious Diseases and Geographical Medicine, Stanford University, Stanford, California.
Robert O OpokaDepartment of Paediatrics, Makerere University College of Health Sciences, Kampala, Uganda.
Edward A LiechtyDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana.
Miriam NakalembeDepartment of Obstetrics and Gynecology, Makerere University College of Health Sciences, Kampala, Uganda.
Moses R KamyaSchool of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.
Grant DorseyDepartment of Medicine, University of California San Francisco, San Francisco, California.
Chandy C JohnDepartment of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana.
Makerere University · UGIndiana University School of MedicineInfectious Diseases Research Collaboration · UGIndiana University – Purdue University Indianapolis · USStanford University · USUniversity of California, San Francisco · US

Funding

The immunologic consequences of prenatal exposure to malariaP01HD059454 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHARLEBOIS, EDWIN DUNCAN · 2008 to 2017
$22.6M
Prophylaxis against malaria to enhance child developmentR01HD086124 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI BANGIRANA, PAUL, JOHN, CHANDY C. · 2016 to 2020
$2.0M
Research training in infection, nutrition and neurodevelopment in UgandaD43TW010928 · FIC · INDIANA UNIVERSITY INDIANAPOLIS · PI Chandy C. John · 2018 to 2026
$1.9M
FIC NIH HHS D43 TW010928NICHD NIH HHS P01 HD059454NICHD NIH HHS R01 HD086124
6 · The paper itself

Abstract

Maternal infection during pregnancy can have lasting effects on neurodevelopment, but the impact of malaria in pregnancy on child neurodevelopment is unknown. We present a case of a 24-year-old gravida three woman enrolled at 14 weeks 6 days of gestation in a clinical trial evaluating malaria prevention strategies in pregnancy. She had two blood samples test positive for

Indexed as

Diseases in TwinsAntimalarialsArtemisininsDevelopmental DisabilitiesFemaleHumansInfantInfant, NewbornMalariaPiperazinesPlacentaPregnancyPregnancy Complications, ParasiticPregnancy OutcomePremature BirthQuinolinesAntimalarialsArtemisininsartenimolpiperaquinePiperazinesQuinolines

Identifiers

PMID30628574
PMCPMC6402896
OpenAlexW2908786923

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.