Evidence map›Paper›PMID 30628573›Full record

Trial reportThe American journal of tropical medicine and hygiene2019

WASH for WORMS: A Cluster-Randomized Controlled Trial of the Impact of a Community Integrated Water, Sanitation, and Hygiene and Deworming Intervention on Soil-Transmitted Helminth Infections.

Susana Vaz Nery, Rebecca J Traub, James S McCarthy, Naomi E Clarke, Salvador Amaral, Stacey Llewellyn, Edmund Weking, Alice Richardson, Suzy J Campbell, Darren J Gray and 4 more

Open access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 5 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 5 syntheses or guidelines pooled it, 44 citations in OpenAlex.

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  5. Anthelmintic drugs for treating ascariasis.The Cochrane database of systematic reviews · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Susana Vaz NeryThe Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia.
Rebecca J TraubFaculty of Veterinary and Agricultural Sciences, University of Melbourne, Melbourne, Australia.
James S McCarthyClinical Tropical Medicine Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Naomi E ClarkeResearch School of Population Health, Australian National University, Canberra, Australia.
Salvador AmaralResearch School of Population Health, Australian National University, Canberra, Australia.
Stacey LlewellynClinical Tropical Medicine Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Australia.
Edmund WekingWaterAid Australia, Dili, Timor-Leste.
Alice RichardsonResearch School of Population Health, Australian National University, Canberra, Australia.
Suzy J CampbellResearch School of Population Health, Australian National University, Canberra, Australia.
Darren J GrayResearch School of Population Health, Australian National University, Canberra, Australia.
Andrew J VallelyThe Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia.
Gail M WilliamsSchool of Public Health, University of Queensland, Brisbane, Australia.
Ross M AndrewsMenzies School of Health Research, Charles Darwin University, Darwin, Australia.
Archie C A ClementsFaculty of Health Sciences, Curtin University, Perth, Australia.
Australian National University · AUQIMR Berghofer Medical Research Institute · AUCurtin University · AUMenzies School of Health Research · AUUniversity of Melbourne · AUUniversity of Queensland · AUUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Water, sanitation, and hygiene (WASH) interventions have been proposed as an important complement to deworming programs for sustainable control of soil-transmitted helminth (STH) infections. We aimed to determine whether a community-based WASH program had additional benefits in reducing STH infections compared with community deworming alone. We conducted the WASH for WORMS cluster-randomized controlled trial in 18 rural communities in Timor-Leste. Intervention communities received a WASH intervention that provided access to an improved water source, promoted improved household sanitation, and encouraged handwashing with soap. All eligible community members in intervention and control arms received albendazole every 6 months for 2 years. The primary outcomes were infection with each STH, measured using multiplex real-time quantitative polymerase chain reaction. We compared outcomes between study arms using generalized linear mixed models, accounting for clustering at community, household, and individual levels. At study completion, the integrated WASH and deworming intervention did not have an effect on infection with

Indexed as

HygieneSanitationAdolescentAdultAnthelminticsChildChild, PreschoolCluster AnalysisFemaleHelminthiasisHumansMalePublic HealthSoilWaterWater SupplyAnthelminticsSoilWater

Identifiers

PMID30628573
PMCPMC6402916
OpenAlexW2910376764

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.