Evidence map›Paper›PMID 30628568›Full record

ArticleThe American journal of tropical medicine and hygiene2019

Japanese Encephalitis- and Dengue-Associated Acute Encephalitis Syndrome Cases in Myanmar.

Aung Kyaw Kyaw, Mya Myat Ngwe Tun, Takeshi Nabeshima, Corazon C Buerano, Tsuyoshi Ando, Shingo Inoue, Daisuke Hayasaka, Chang-Kweng Lim, Masayuki Saijo, Hlaing Myat Thu and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. A need to raise the bar - A systematic review of temporal trends in diagnostics for Japanese encephalitis virus infection, and perspectives for future research.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
    Pooled it
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Aung Kyaw KyawDepartment of Medical Research (Pyin Oo Lwin Branch), Ministry of Health and Sports, Pyin Oo Lwin, Mandalay Region, Myanmar.
Mya Myat Ngwe TunDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
Takeshi NabeshimaDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
Corazon C BueranoResearch and Biotechnology, St. Luke's Medical Center, Quezon City, Philippines.
Tsuyoshi AndoDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
Shingo InoueDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
Daisuke HayasakaDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
Chang-Kweng LimDepartment of Virology I, National Institute of Infectious Diseases, Tokyo, Japan.
Masayuki SaijoDepartment of Virology I, National Institute of Infectious Diseases, Tokyo, Japan.
Hlaing Myat ThuDepartment of Medical Research (Pyin Oo Lwin Branch), Ministry of Health and Sports, Pyin Oo Lwin, Mandalay Region, Myanmar.
Kyaw Zin ThantDepartment of Medical Research (Pyin Oo Lwin Branch), Ministry of Health and Sports, Pyin Oo Lwin, Mandalay Region, Myanmar.
Kouichi MoritaDepartment of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
Nagasaki University · JPMinistry of Health and Sports · MMNational Institute of Infectious Diseases · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was conducted to find the burden of dengue virus (DENV) and Japanese encephalitis virus (JEV) among children under the age of 13, who presented with acute encephalitis syndrome at Mandalay Children Hospital in Myanmar in 2013. Molecular and serological investigations were performed on 123 cerebrospinal fluid (CSF) samples collected from these patients. By neutralization tests and/or virus isolation, four (3.3%) JEV- and one DENV-associated encephalitis cases (0.8%) were confirmed. Antibody titer against JEV Genotype 3 was the highest among the laboratory-confirmed JEV cases. One strain of DENV-1 with Genotype 1 was isolated from the CSF sample of the dengue encephalitis patient; this was similar to the virus circulating in the study area and neighboring countries. This study shows that flaviviruses are important pathogens causing encephalitis in Myanmar. Active disease surveillance, vector control, and vaccination programs should be enforced to reduce the morbidity and mortality caused by flavivirus encephalitis.

Indexed as

Antibodies, ViralChildChild, PreschoolDengueDengue VirusEncephalitis, JapaneseEnzyme-Linked Immunosorbent AssayFemaleHumansInfantMaleMyanmarNeutralization TestsPhylogenyAntibodies, Viral

Identifiers

PMID30628568
PMCPMC6402905
OpenAlexW2909315524

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.