ArticleThe American journal of tropical medicine and hygiene2019
Etiologies of Acute Undifferentiated Febrile Illness in Bangkok, Thailand.
Article in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07432061 (Prediction of Infectious Diseases in LMICs Using Electronic Health Record Data), which is not on this map. Cited by 46 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prediction of Infectious Diseases in LMICs Using Electronic Health Record Data
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic accuracy of the WHO clinical definitions for dengue and implications for surveillance: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2021Pooled it
- Clinical and Laboratory Features of Scrub Typhus among Adult Patients with Acute Febrile Illness in Tak and Nakhon Phanom Provinces, Thailand, 2017-2020.The American journal of tropical medicine and hygiene · 2026Article
- Climatic determinants of antibiotic use in Southern Thailand: Retrospective longitudinal study during 2021 to 2023.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Performance evaluation of TaqMan Array Card real-time PCR for multi-pathogen detection in acute undifferentiated febrile illness.BMC infectious diseases · 2026Article
- Francisella spp. as an overlooked cause of acute undifferentiated febrile illness in Colombia? Unexpected evidence from febrile patients negative for other common and neglected etiologies in Villeta municipality.Tropical medicine and health · 2026Article
- Antibiotic utilization pattern and its associated factors based on WHO AWaRe classification at a university hospital in the South of Thailand.Journal of pharmaceutical policy and practice · 2026Article
- When Fever Turns Hemorrhagic in the Maldives: A Case Report of Dengue in a G6PD-Deficient Young Adult With Hemolysis and Rhabdomyolysis.Case reports in infectious diseases · 2026Article
- Clinical Profile, Syndromic Classification, and Studying the Seasonal Variation and Geo-mapping of the Patients with Febrile Illness Reporting to a Primary Health Center in Puducherry.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2025Article
- Effectiveness of Antibiotic Regimens in Reducing White Blood Cell Count Within Three to Five Days in Febrile Leukocytosis Treated With Ambulatory Therapy.Journal of clinical medicine research · 2025Article
- Malaria, Dengue Fever, and Leptospirosis in the Urabá Antioqueño Region, Colombia: Etiological and Molecular Characterization among Patients with Acute Undifferentiated Febrile Illness.The American journal of tropical medicine and hygiene · 2025Article
- Epidemiological Changes in Acute Febrile Diseases after the COVID-19 Pandemic in Thailand.The American journal of tropical medicine and hygiene · 2025Article
- Molecular and serological investigation of hepatitis B virus in patients with acute undifferentiated febrile illness at Tha Song Yang hospital, Tak Province, Thailand.BMC infectious diseases · 2025Article
- Article
- Rickettsiosis Infections in Sarawak: Epidemiological Insights and Public Health Strategies.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025Review
- Diagnosis and Clinical Description of Leptospirosis Cases Identified Through Hospital-Based Active Surveillance in Puerto Rico, 2019-2021.Journal of tropical medicine · 2025Article
- Clinical and Epidemiological Characteristics of Chikungunya and Dengue Infections in Provincial Hospitals of Davao de Oro, Philippines.Reports (MDPI) · 2024Article
- Evaluating Antibiotic Misuse and Cost Analysis Among Hospitalized Dengue Virus-Infected Adults: Insights From a Retrospective Cohort Study.Open forum infectious diseases · 2024Article
- Demographic and Clinical Factors Associated with Bacterial or Nonbacterial Etiologies of Acute Undifferentiated Febrile Illness: Findings from a 3-Year Observational Study in Thailand, 2017-2020.The American journal of tropical medicine and hygiene · 2024Observational
- Article
- Febrile Rash: An Early Diagnostic Clue to Infectious Illness in Travelers Returning from Thailand.Reports (MDPI) · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute undifferentiated febrile illness (AUFI) has been a diagnostic dilemma in the tropics. Without accurate point-of-care tests, information on local pathogens and clinical parameters is essential for presumptive diagnosis. A prospective hospital-based study was conducted at the Bangkok Hospital for Tropical Diseases from 2013 to 2015 to determine common etiologies of AUFI. A total of 397 adult AUFI cases, excluding malaria by blood smear, were enrolled. Rapid diagnostic tests for tropical infections were performed on admission, and acute and convalescent samples were tested to confirm the diagnosis. Etiologies could be identified in 271 (68.3%) cases. Dengue was the most common cause, with 157 cases (39.6%), followed by murine typhus (20 cases; 5.0%), leptospirosis (16 cases; 4.0%), influenza (14 cases; 3.5%), and bacteremia (six cases; 1.5%). Concurrent infection by at least two pathogens was reported in 37 cases (9.3%). Furthermore, characteristics of dengue and bacterial infections (including leptospirosis and rickettsioses) were compared to facilitate dengue triage, initiate early antibiotic treatment, and minimize unnecessary use of antibiotics. In conclusion, dengue was the most common pathogen for AUFI in urban Thailand. However, murine typhus and leptospirosis were not uncommon. Empirical antibiotic treatment using doxycycline or azithromycin might be more appropriate, but cost-benefit studies are required. Physicians should recognize common causes of AUFI in their localities and use clinical and laboratory clues for provisional diagnosis to provide appropriate treatment while awaiting laboratory confirmation.
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