Evidence map›Paper›PMID 30628468›Full record

ArticlePsychology, health & medicine2019

Factors influencing parental trust in medical researchers for child and adolescent patients' clinical trial participation.

Jennifer Cunningham-Erves, Jason Deakings, Tilicia Mayo-Gamble, Kendria Kelly-Taylor, Stephania T Miller

Abstract read
In one paragraph

Article in Psychology, health & medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Digital Tools and Strategies for Engaging Patients in Cancer Clinical Trials.Cancer control : journal of the Moffitt Cancer Center
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jennifer Cunningham-Ervesa Department of Internal Medicine , Meharry Medical College , Nashville , TN , USA.
Jason Deakingsb School of Graduate Studies and Research , Meharry Medical College , Nashville , TN , USA.
Tilicia Mayo-Gamblec Department Community Health Behavior and Education , Georgia Southern University , Statesboro , GA , USA.
Kendria Kelly-Taylorb School of Graduate Studies and Research , Meharry Medical College , Nashville , TN , USA.
Stephania T Millerd Department of Surgery , Meharry Medical College , Nashville , TN , USA.

Funding

VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Technologies and Resources CoreU54MD007593 · NIMHD · MEHARRY MEDICAL COLLEGE · PI ADUNYAH, SAMUEL EVANS · 2012 to 2018
$24.7M
NCATS NIH HHS UL1 TR000445NCRR NIH HHS UL1 RR024975NIMHD NIH HHS U54 MD007593
6 · The paper itself

Abstract

Parental trust in medical researchers is a commonly cited barrier to their child's participation in clinical research. Yet, there is little understanding of factors influencing parental trust to be implemented in interventions to address their concerns. This study seeks to identify psychosocial and modifying factors influencing parental trust in medical researchers to improve child and adolescent patients clinical trial participation, and potentially their health outcomes. We conducted a cross-sectional study with 307 parents. Multiple ordinary linear (OLS) regression was conducted to determine: (1) psychosocial and modifying factors associated with parental trust; and (2) perceived advantages and disadvantages associated with parental trust. Parent's race (White) (β = .343, p < .001), higher education level (β = .409, p < .001), higher perceived advantages of adolescent clinical trials (β = .142, p < .001), and lower perceived disadvantages of adolescent clinical trials (β = -.337, p = .001) were the most significant predictors of higher levels of parental trust in medical researchers. Parents who were African American and had lower education levels expressed lower levels of trust in medical researchers. Education on the benefits of clinical trials could reduce parents' apprehension towards their child's participation in clinical trials. Results support the development of a clinical trial education program for parents to improve their trust in medical researchers.

Indexed as

AdolescentAdultBlack or African AmericanChildClinical Trials as TopicCross-Sectional StudiesFemaleHumansMaleParentsPatient ParticipationResearcher-Subject RelationsTrustChildren and adolescentsclinical trialsmedical researchersparent trustpsychosocial and modifying factors

Identifiers

PMID30628468
PMCPMC6483829

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.