ArticleCancer medicine2019
Marital status and survival in patients with soft tissue sarcoma: A population-based, propensity-matched study.
Article in Cancer medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Marital status and survival in cancer patients: A systematic review and meta-analysis.Cancer medicine · 2023Pooled it
- Development and validation of tumor-size-stratified prognostic nomograms for patients with uterine sarcoma: A SEER database analysis.Cancer medicine · 2023Trial
- Development and Validation of a Prognostic Nomogram for Lung Adenocarcinoma: A Population-Based Study.Journal of healthcare engineering · 2022Trial
- Clinical Significance of Marital Status and Changes in Status Extracted from Unstructured Clinical Notes Using Ensembles of Off-the-Shelf Extraction Models.Research square · 2025Article
- Clinical features and demographic characteristics of gestational trophoblastic neoplasia: Single center experience and the SEER database.Biomolecules & biomedicine · 2024Article
- Managing sleep disruptions during cancer: Practical tips for patient education.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2024Article
- How to use the Surveillance, Epidemiology, and End Results (SEER) data: research design and methodology.Military Medical Research · 2023Review
- Construction and validation of a nomogram model to predict the overall survival rate of esophageal cancer patients receiving neoadjuvant chemotherapy: A population-based study.Frontiers in surgery · 2022Article
- Article
- Risk analysis of pulmonary metastasis of chondrosarcoma by establishing and validating a new clinical prediction model: a clinical study based on SEER database.BMC musculoskeletal disorders · 2021Article
- Marital status impacts survival in patients with upper tract urothelial carcinoma: a population-based, propensity-matched study.Translational andrology and urology · 2020Article
- Influence of marital status on overall survival in adult patients with chordoma: a SEER-based study.Journal of orthopaedic surgery and research · 2020Article
- Marital status, an independent predictor for survival of gastric neuroendocrine neoplasm patients: a SEER database analysis.BMC endocrine disorders · 2020Article
- The Influence of Marital Status on the Survival of Patients with Uveal Melanoma.Journal of ophthalmology · 2020Article
- The contemporary trend in worsening prognosis of pancreatic acinar cell carcinoma: A population-based study.PloS one · 2020Article
- Risk Factors for Incidence and Prognosis in Chondrosarcoma Patients with Pulmonary Metastasis at Initial Diagnosis.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Marital Status and Survival in Osteosarcoma Patients: An Analysis of the Surveillance, Epidemiology, and End Results (SEER) Database.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Marital status and survival in patients with soft tissue sarcoma: A population-based, propensity-matched study.Cancer medicine · 2019Article
- Score for the Overall Survival Probability of Patients With First-Diagnosed Distantly Metastatic Cervical Cancer: A Novel Nomogram-Based Risk Assessment System.Frontiers in oncology · 2019Article
- A real-world 1:1 propensity-matched study revealed unmarried status was independently associated with worse survival for patients with renal clear cell carcinoma.Journal of Cancer · 2019Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMarital status serves as an independent prognostic factor for survival in a variety of cancers. However, its prognostic impact on soft tissue sarcoma (STS) has not yet been established.
objectiveTo investigate the impact of marital status on survival outcomes among STS patients.
methodsA total of 18 013 STS patients diagnosed between 2004 and 2015 were extracted from Surveillance, Epidemiology, and End Results (SEER) database. The marital status was classified into married, divorced, widowed, and single. Kaplan-Meier analysis and multivariate Cox proportional hazards regression analysis were conducted to establish the impact of marital status on the overall survival (OS) and cancer-specific survival (CSS). Subgroup analyses were conducted based on age, SEER historic stage and surgery condition. Propensity score matching (PSM) was used to perform a 1:1 matched-pair analysis to minimize the group differences caused by covariates.
resultsMarried patients enjoyed better 5-year overall survival (OS) and 5-year cancer-specific survival (CSS), compared with patients who were divorced, widowed, and single, respectively. Multivariate Cox proportional hazards regression analysis revealed that marital status was an independent prognostic and protective factor for survival among STS patients, and unmarried status was associated with higher mortality hazards for both OS and CSS. Additionally, widowed individuals had the highest risks of overall and cancer-specific mortality compared to other unmarried groups. In the subgroup analyses, similar associations were also found. Furthermore, marital status still remained an independent prognostic and protective factor for both OS and CSS even in 1:1 matched-pair analysis.
conclusionsMarital status was an independent prognostic and protective factor for survival for STS patients. Widowed patients suffered the highest death risks among the unmarried groups.
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