Evidence map›Paper›PMID 30627992›Full record

ArticleJournal of assisted reproduction and genetics2019

In assisted reproduction by IVF or ICSI, the rate at which embryos develop to the blastocyst stage is influenced by the fertilization method used: a split IVF/ICSI study.

Barbara Speyer, Helen O'Neill, Wael Saab, Srividya Seshadri, Suzanne Cawood, Carleen Heath, Matthew Gaunt, Paul Serhal

Abstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Prediction of Fertilization Disorders in theFrontiers in endocrinology · 2022
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Barbara SpeyerInstitute for Women's Health, University College London, London, UK. betsmithuk@yahoo.co.uk.ORCID http://orcid.org/0000-0002-3901-8641
Helen O'NeillInstitute for Women's Health, University College London, London, UK.
Wael SaabCentre for Reproductive and Genetic Health, London, UK.
Srividya SeshadriCentre for Reproductive and Genetic Health, London, UK.
Suzanne CawoodCentre for Reproductive and Genetic Health, London, UK.
Carleen HeathCentre for Reproductive and Genetic Health, London, UK.
Matthew GauntCentre for Reproductive and Genetic Health, London, UK.
Paul SerhalCentre for Reproductive and Genetic Health, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare in vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI) in regard to post-fertilization development and outcome with the purpose of ascertaining the most effective fertilization method for assisted reproduction.

methodsA retrospective cohort study of 136 split IVF/ICSI cycles (where sibling oocytes are fertilized by two different methods using the same sperm sample).

resultsIVF-derived embryos developed to the blastocyst stage at a significantly faster rate than ICSI-derived embryos. There was no significant difference in fertilization or livebirth rates between the two fertilization methods.

conclusionsFor patients with sperm progressive motility ≥ 1.0 × 10

Indexed as

Reproductive Techniques, AssistedAdultBlastocystEmbryonic DevelopmentEmbryo TransferFemaleFertilization in VitroHumansInfertilityLive BirthMaleOocytesPregnancyPregnancy RateSpermatozoaSperm Injections, IntracytoplasmicEmbryo developmentICSIIVF

Identifiers

PMID30627992
PMCPMC6504986

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.